Results 21 to 30 of about 349,548 (267)
Pooled DNA genotyping on Affymetrix SNP genotyping arrays
BMC Genomics, 2006 Background Genotyping technology has advanced such that genome-wide association studies of complex diseases based upon dense marker maps are now technically feasible. However, the cost of such projects remains high.
Owen Michael J +5 more
doaj +1 more source
Genotyping—From Genomic DNA to Genotype in a Single Tube [PDF]
Angewandte Chemie International Edition, 2005 AbstractNucleotide variations in the human genome, such as single‐nucleotide polymorphisms, have been researched more intensively since it became apparent that these deviations are linked to various diseases and also several side effects of drugs. The investigation of genomic DNA in the laboratory requires routine methods that are time‐, labour‐, and ...
Strerath, Michael, Marx, Andreas
openaire +3 more sources
Nature Communications, 2018 Association between variants in 11 different genes and breast cancer risk has been established and sequencing of these genes is recommended to provide personalized diagnosis, therapy, and surveillance for the high-risk patients and their relatives.
Yukihide Momozawa +14 more
doaj +1 more source
Identification of Putative Novel Rotavirus H VP7, VP4, VP6 and NSP4 Genotypes in Pigs
Viruses, 2023 Rotavirus H (RVH) has been detected in humans, pigs and bats. Recently, RVH infections were reported in different porcine farms worldwide, suggesting epidemiological relevance.
Elena Ferrari +6 more
doaj +1 more source
Genetic variability of the regulatory region of the FSH-β gene and its association with reproductive traits in Nellore bulls [PDF]
Iraqi Journal of Veterinary SciencesMolecular biology techniques are important tools for studying animal health and production characteristics. Thus, determining the genotypes of animals with high genetic value enables the implementation of genetic improvement programs, especially related ...
Lorena K. Silva +7 more
doaj +1 more source
Feasibility of High-Throughput Genome-Wide Genotyping using DNA from Stored Buccal Cell Samples
Biomarker Insights, 2010 It is unclear if buccal cell samples contain sufficient human DNA with adequately sized fragments for high throughput genetic bioassays. Yet buccal cell sample collection is an attractive alternative to gathering blood samples for genetic epidemiologists
Stephanie J. Loomis +12 more
doaj +1 more source
Transference of the Term "Genotype" [PDF]
Science, 1911 n ...
Bather, F. A., Calman, W. T.
openaire +3 more sources
Priors for Genotyping Polyploids [PDF]
Bioinformatics, 2019 Abstract Motivation Empirical Bayes techniques to genotype polyploid organisms usually either (i) assume technical artifacts are known a priori or (ii) estimate technical artifacts simultaneously with the prior genotype distribution.
Gerard, David +1 more
openaire +2 more sources
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge +6 more
wiley +1 more source