Results 21 to 30 of about 612,806 (292)

VISMapper: ultra-fast exhaustive cartography of viral insertion sites for gene therapy

open access: yesBMC Bioinformatics, 2017
Background The possibility of integrating viral vectors to become a persistent part of the host genome makes them a crucial element of clinical gene therapy.
José M. Juanes   +7 more
doaj   +1 more source

In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-up. [PDF]

open access: yes, 2004
To determine the optimum duration of follow-up for the assessment of drug efficacy against Plasmodium falciparum malaria, 96 trial arms from randomized controlled trials (RCTs) with follow-up of 28 days or longer that were conducted between 1990 and 2003
Stepniewska, K   +16 more
core   +2 more sources

The Role of Family-Based Designs in Genome-Wide Association Studies [PDF]

open access: yes, 2009
Genome-Wide Association Studies (GWAS) offer an exciting and promising new research avenue for finding genes for complex diseases. Traditional case-control and cohort studies offer many advantages for such designs.
Laird, Nan M., Lange, Christoph
core   +1 more source

Genotyping

open access: yesEgyptian Journal of Aquatic Research, 2014
Culture-independent 16S rRNA gene analysis approach was used to explore and evaluate archaea in a polluted site, El-Zeitia, Suez Gulf, Egypt. Metagenomic DNA was extracted from a sediment sample.
Hosam Easa Elsaied
doaj   +1 more source

Phenotypic screening and molecular characterization of cassava mosaic disease resistance in Côte d'Ivoire cassava germplasm

open access: yesFrontiers in Sustainable Food Systems, 2023
Cassava is the staple food crop for hundreds of millions of people in Africa. In Côte d'Ivoire, it is a main source of calories for over 26 million people.
William J-L. Amoakon   +14 more
doaj   +1 more source

Development of a Next-Generation NIL Library in Arabidopsis Thaliana for Dissecting Complex Traits [PDF]

open access: yes, 2013
The identification of the loci and specific alleles underlying variation in quantitative traits is an important goal for evolutionary biologists and breeders.
Bauerle, William L.   +8 more
core   +3 more sources

Tetra‐primer amplification refractory mutation system (ARMS) PCR used to detect 3’UTR rs1948 mutation in CHRNB4

open access: yesIndonesian Journal of Biotechnology, 2022
Rs1948 A>G is a single nucleotide variation (SNV) in the 3’‐UTR of CHRNB4. Genotyping the synonymous CHRNB4 rs1948 may be useful in identifying a lung cancer susceptibility gene.
Anggi Laksmita Dewi   +2 more
doaj   +1 more source

Comparison of genotyping methods and toxin gene profiles of Staphylococcus aureus isolates from clinical specimens [PDF]

open access: yesGenetics and Molecular Biology, 2023
Staphylococcus aureus is a frequent cause of infections worldwide. Methicillin-resistant S. aureus (MRSA) is one of the main causes of Gram-positive infections, and methicillin-susceptible strains (MSSA) primarily colonize and infect community hosts ...
Mariana Andrade-Figueiredo   +3 more
doaj   +1 more source

The genetics of cardiovascular disease [PDF]

open access: yes, 2008
Recent advances in genotyping technology and insights into disease mechanisms have increased interest in the genetics of cardiovascular disease. Several candidate genes involved in cardiovascular diseases were identified from studies using animal models,
Abu-Amero   +72 more
core   +1 more source

Pooled DNA genotyping on Affymetrix SNP genotyping arrays

open access: yesBMC Genomics, 2006
Background Genotyping technology has advanced such that genome-wide association studies of complex diseases based upon dense marker maps are now technically feasible. However, the cost of such projects remains high.
Owen Michael J   +5 more
doaj   +1 more source

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