Results 31 to 40 of about 612,806 (292)

Human streptococcus agalactiae strains in aquatic mammals and fish [PDF]

open access: yes, 2013
<p>Background: In humans, Streptococcus agalactiae or group B streptococcus (GBS) is a frequent coloniser of the rectovaginal tract, a major cause of neonatal infectious disease and an emerging cause of disease in non-pregnant adults.
Crumlish, M.   +7 more
core   +5 more sources

Germline pathogenic variants of 11 breast cancer genes in 7,051 Japanese patients and 11,241 controls

open access: yesNature Communications, 2018
Association between variants in 11 different genes and breast cancer risk has been established and sequencing of these genes is recommended to provide personalized diagnosis, therapy, and surveillance for the high-risk patients and their relatives.
Yukihide Momozawa   +14 more
doaj   +1 more source

Quality of DNA extracted from formalin-fixed, paraffin-embedded canine tissues. [PDF]

open access: yes, 2020
Veterinary pathology tissue banks are valuable resources for genetic studies. However, limited data exist as to whether quality DNA can be extracted from these tissues for use in canine genotyping studies.
Bannasch, Danika L   +2 more
core   +1 more source

Developing a Molecular Identification Assay of Old Landraces for the Genetic Authentication of Typical Agro-Food Products: The Case Study of the Barley ‘Agordino’

open access: yesFood Technology and Biotechnology, 2017
The orzo Agordino is a very old local variety of domesticated barley (Hordeum vulgare ssp. distichum L.) that is native to the Agordo District, Province of Belluno, and is widespread in the Veneto Region, Italy. Seeds of this landrace are widely used for
Fabio Palumbo   +2 more
doaj   +1 more source

The efficacy of diuretics in complex treatment of patients with hypertension according to the Gly460Trp polymorphism of the α-adducin gene

open access: yesZaporožskij Medicinskij Žurnal, 2021
The aim of the study was to investigate the effect of thiazide diuretics on blood pressure (BP) depending on Gly460Trp ADD1 gene polymorphism in arterial hypertension (AH) patients of the Ukrainian population in order to predict their individual ...
S. A. Yermolenko   +5 more
doaj   +1 more source

Single nucleotide recognition using a probes-on-carrier DNA chip

open access: yesBioTechniques, 2019
Following the sequencing of the human genome, SNP analysis of individual patients has become essential for achieving the best drug response and ensuring optimal care.
Satoshi Fuke   +2 more
doaj   +1 more source

Feasibility of High-Throughput Genome-Wide Genotyping using DNA from Stored Buccal Cell Samples

open access: yesBiomarker Insights, 2010
It is unclear if buccal cell samples contain sufficient human DNA with adequately sized fragments for high throughput genetic bioassays. Yet buccal cell sample collection is an attractive alternative to gathering blood samples for genetic epidemiologists
Stephanie J. Loomis   +12 more
doaj   +1 more source

Using GWAS Data to Identify Copy Number Variants Contributing to Common Complex Diseases

open access: yes, 2010
Copy number variants (CNVs) account for more polymorphic base pairs in the human genome than do single nucleotide polymorphisms (SNPs). CNVs encompass genes as well as noncoding DNA, making these polymorphisms good candidates for functional variation ...
Teslovich, Tanya M., Zöllner, Sebastian
core   +1 more source

Methods for Scarless, Selection-Free Generation of Human Cells and Allele-Specific Functional Analysis of Disease-Associated SNPs and Variants of Uncertain Significance. [PDF]

open access: yes, 2017
With the continued emergence of risk loci from Genome-Wide Association studies and variants of uncertain significance identified from patient sequencing, better methods are required to translate these human genetic findings into improvements in public ...
Carvajal-Carmona, Luis G   +4 more
core   +4 more sources

PCR Based Genotyping of Lulu Cattle of Nepal for A1, A2 Type Beta-caseins [PDF]

open access: yes, 2020
Lulu is an indigenous breed of cattle (Bos taurus) found in high altitude regions of western Nepal. Population of Lulu cattle has been declining due to introgression with other exotic breeds to increase milk productivity.
Budhathoki, N. (Nabina)   +7 more
core  

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