Results 161 to 170 of about 10,219,641 (384)
Inferring genotyping error rates from genotyped trios [PDF]
arXiv, 2011 Genotyping errors are known to influence the power of both family-based and case-control studies in the genetics of complex disease. Estimating genotyping error rate in a given dataset can be complex, but when family information is available error rates can be inferred from the patterns of Mendelian inheritance between parents and offspring.
arxiv
Advanced Science, EarlyView.MeCP2 lactylation protects against ischemic stroke by reducing brain infarct volume and improving neurological outcomes. Lactylation at K210/K249 exerts neuroprotective effects by repressing the transcription of apoptosis‐associated genes, including Pdcd4 and Pla2g6. HDAC3 and p300 serve as key regulatory enzymes for MeCP2 lactylation following stroke.
Min Sun +13 more
wiley +1 more source
Variant genotyping with gap filling.
PLoS ONE, 2017 Although recent developments in DNA sequencing have allowed for great leaps in both the quality and quantity of genome assembly projects, de novo assemblies still lack the efficiency and accuracy required for studying genetic variation of individuals ...
Riku Walve, Leena Salmela, Veli Mäkinen
doaj +1 more source
Evaluation of Detached Shoot and Leaflet Inoculation Techniques to Screen Peanut Genotypes for Resistance to Rhizoctonia Limb Rot [PDF]
, 2001 Maximilian Franke, T. B. Brenneman
openalex +1 more source
Learnable Group Transform: Enhancing Genotype-to-Phenotype Prediction for Rice Breeding with Small, Structured Datasets [PDF]
arXivGenotype-to-Phenotype (G2P) prediction plays a pivotal role in crop breeding, enabling the identification of superior genotypes based on genomic data. Rice (Oryza sativa), one of the most important staple crops, faces challenges in improving yield and resilience due to the complex genetic architecture of agronomic traits and the limited sample size in ...
arxiv
Advanced Science, EarlyView.New research reveals that oxytocin signaling during the early postnatal period is critical for regulating brain development and social behavior. Selectively suppressing oxytocin neurons by chemogenetic method shows that early—but not late—disruption leads to autism‐like behaviors.
Zi‐Hui Wang +10 more
wiley +1 more source
Вавиловский журнал генетики и селекции, 2015 Tracing of transmission routes and identification of pathogen sources are important issues in preventive measures aimed at controlling human and animal infectious diseases.
V. P. Terletskiy +5 more
doaj +1 more source
COMPARISON OF RAPID METHOD OF DNA EXTRACTION USING MICROWAVE IRRADIATION WITH CONVENTIONAL PHENOL CHLOROFORM TECHNIQUE FOR USE IN MULTIPLEX PCR FOR mec A AND fem B GENES TO IDENTIFY GENOTYPES OF MRSA FROM CULTURES [PDF]
, 2001 PK MENON, A Nagendra
openalex +1 more source
Advanced Science, EarlyView.The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang +12 more
wiley +1 more source
A novel technique based on a PNA hybridization probe and FRET principle for quantification of mutant genotype in fibrous dysplasia/McCune-Albright syndrome [PDF]
, 2004 Abdullah Karadağ
openalex +1 more source