Results 151 to 160 of about 11,640,365 (320)

Sulfakinin Signaling Sense Circulating Fructose and Suppresses Food Consumption via Insulin‐Like Peptide in Bactrocera Dorsalis

Advanced Science, EarlyView.
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li, Bao Dong, Zheng‐Lin Ren, Xue‐Guang Zhu, Quan Lei, Yoonseong Park, Jin‐Jun Wang, Hong‐Bo Jiang   +7 more
wiley   +1 more source

Results of highlighting genes associated with ethylene production in apple genotypes cultivated in Romania

Romanian Journal of Horticulture
Molecular screening using SSLP and CAPS techniques enabled the genotyping of 40 apple cultivars developed at the main national research centres in Romania.
Adina Floricica Iancu, Mădălina Militaru, Sina Niculina Cosmulescu   +2 more
doaj   +1 more source

Performance analysis of methods to infer missing genotypes [PDF]

, 2008
Complex analyses such as genetic mapping, disease association studies, disease mapping in the context of environmental health and environmental epidemiology studies rely on high-throughput genotyping techniques.
Sinoquet, Christine
core   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

MODERN METHODS APPLICATION OF GENOTYPING OF INFECTIOUS DISEASES PATHOGENS IN THE CONTEXT OF OPERATIONAL WORK OF SPECIALIZED ANTI-EPIDEMIC TEAM DURING THE XXII OLYMPIC WINTER GAMES AND XI PARALYMPIC WINTER GAMES

Журнал микробиологии, эпидемиологии и иммунобиологии, 2015
This paper considers the experience of genotyping and sequencing technologies in laboratories of specialized anti-epidemic team (SAET) during the XXII Olympic Winter Games and XI Paralympic Winter Games of 2014 in Sochi.
B. P Kuzkin, A. N Kulichenko, A. S Volynkina, D. V Efremenko, I. V Kuznetsova, E. S Kotenev, G. I Lyamkin, N. N Kartsev, V. P Klindukhov   +8 more
doaj  

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

REPRODUCTIVE SUCCESS IN HATCHERY-PRODUCED EASTERN OYSTER, CRASSOSTREA VIRGINICA (GMELIN) [PDF]

, 2014
The eastern oyster (Crassostrea virginica Gmelin 1791) has great ecological and economic importance but populations have declined, especially in Chesapeake Bay, to historically low numbers.
Piggott, April
core   +1 more source

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

Advanced Science, EarlyView.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu, Xuedi Zhang, Ying Zhou, Jie Zheng, Angyang Sun, Kailong Zhuang, Weiwei Bao, Guanjun Gao   +7 more
wiley   +1 more source

Beijing genotype is the most dominant genotype among clinical isolates of m.tuberculosis in Kazakhstan [PDF]

, 2014
Methods of genotyping of M. tuberculosis play important role in tuberculosis (TB) infection control. These techniques are used to detect or exclude laboratory errors, control recurrent cases and determine ways of TB transmission.
Akhmetova, А., Akilzhanova, A., Bismilda, V., Chingissova, L., Kozhamkulov, U.   +4 more
core   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source