Results 11 to 20 of about 220 (117)

ChnagG Plays the Role of 5-Salicylate Hydroxylase in the Gentisic Acid Pathway of Salicylic Acid Metabolism in Cochliobolus heterostrophus. [PDF]

Mol Plant Pathol
The ChnagG gene in Cochliobolus heterostrophus encodes 5‐salicylate hydroxylase, converting salicylic acid (SA) to gentisic acid, enhancing pathogenicity and suppressing plant SA signalling‐mediated defences during infection. ABSTRACT Salicylic acid (SA) plays a crucial role in the defence strategies of plants against fungal pathogens.
Xu Y, Wei H, Li H, Zeng F, Liu N, Cao Z, Dong J.   +6 more
europepmc   +2 more sources

Bringing up to date the toolkit for the catabolism of aromatic compounds in fungi: The unexpected 1,2,3,5-tetrahydroxybenzene central pathway. [PDF]

Microb Biotechnol
Our understanding of how fungi utilize gallate or other syringyl derivatives is, to date, scarce and mostly relies on unproven assumptions. This study demonstrates the existence of a new 1,2,3,5‐tetrahydroxybenzene central pathway for the catabolism of gallate and related compounds in numerous fungi.
Martins TM, Bento A, Martins C, Tomé AS, Moreira CJS, Silva Pereira C.   +5 more
europepmc   +2 more sources

The salicylate 1,2-dioxygenase from Pseudaminobacter salicylatoxidans DSM 6986T is a bifunctional enzyme that inactivates the mycotoxin ochratoxin A by a novel amidohydrolase activity

, 2023
The salicylate 1,2-dioxygenase from the bacterium Pseudaminobacter salicylatoxidans DSM 6986T (PsSDO) is a versatile metalloenzyme that participates in the aerobic biodegradation of aromatic compounds, such as gentisates and salicylates.
Plaza-Vinuesa, Laura, De Las Rivas, Blanca, Mancheño, Jose M., Muñoz, Rosario, Sánchez-Arroyo, Ana   +4 more
core   +1 more source

Expanding Antarctic biogeography: microbial ecology of Antarctic island soils

Ecography, Volume 2023, Issue 9, September 2023., 2023
The majority of islands surrounding the Antarctic continent are poorly characterized in terms of microbial macroecology due to their remote locations, geographical isolation and access difficulties. The 2016/2017 Antarctic Circumnavigation Expedition (ACE) provided unprecedented access to a number of these islands.
Pedro H. Lebre, Jason Bosch, Clément Coclet, Rebecca Hallas, Ian D. Hogg, Jenny Johnson, Katherine L. Moon, Max Ortiz, Adeola Rotimi, Mark I. Stevens, Gilda Varliero, Peter Convey, Surendra Vikram, Steven L. Chown, and Don A. Cowan   +14 more
wiley   +1 more source

Crystal structure of the monocupin ring‐cleaving dioxygenase 5‐nitrosalicylate 1,2‐dioxygenase from Bradyrhizobium sp.

Acta Crystallographica Section D, Volume 79, Issue 7, Page 632-640, July 2023., 2023
The crystal structure of the monocupin 5‐nitrosalicylate 1,2‐dioxygenase, an iron(II)‐dependent ring‐cleaving dioxygenase, from Bradyrhizobium sp. was determined by molecular replacement using a theoretical model obtained by AlphaFold2. Comparison with structures of other members of the same class and docking of the substrate allowed identification of ...
Erik Eppinger, Andreas Stolz, Marta Ferraroni   +2 more
wiley   +1 more source

Emerging roles for thiol dioxygenases as oxygen sensors

The FEBS Journal, Volume 289, Issue 18, Page 5426-5439, September 2022., 2022
Thiol dioxygenases (TDOs) catalyse oxidation of thiols to sulphinates. Recent reports identify TDOs which catalyse oxidation of N‐terminal cysteine residues of protein substrates in an O2‐sensitive manner, promoting degradation: N‐terminal cysteinyl dioxygenases (NCOs). These appear to form a separate subclass of TDO from those which catalyse oxidation
Dona M. Gunawardana, Karen C. Heathcote, Emily Flashman   +2 more
wiley   +1 more source

A structurally unique Fusobacterium nucleatum tannase provides detoxicant activity against gallotannins and pathogen resistance

Microbial Biotechnology, Volume 15, Issue 2, Page 648-667, February 2022., 2022
A new tannase enzyme from the cancer‐related pathogen Fusobacterium nucleatum is important for the survival of the bacteria under the stress conditions derived from the presence of dietary gallotannins. Using structural studies and molecular modelling we describe new structural features for this enzyme.
José Miguel Mancheño, Estíbaliz Atondo, Julen Tomás‐Cortázar, José Luís Lavín, Laura Plaza‐Vinuesa, Itziar Martín‐Ruiz, Diego Barriales, Ainhoa Palacios, Claudio Daniel Navo, Leticia Sampedro, Ainize Peña‐Cearra, Miguel Ángel Pascual‐Itoiz, Janire Castelo, Ana Carreras‐González, Donatello Castellana, Aize Pellón, Susana Delgado, Patricia Ruas‐Madiedo, Blanca de las Rivas, Leticia Abecia, Rosario Muñoz, Gonzalo Jiménez‐Osés, Juan Anguita, Héctor Rodríguez   +23 more
wiley   +1 more source

Salicylate 1,2-Dioxygenase from Pseudaminobacter salicylatoxidans: Crystal Structure of a Peculiar Ring-cleaving Dioxygenase

, 2008
The crystallographic structure of salicylate 1,2-dioxygenase (SDO), a new ring fission dioxygenase from the naphthalenesulfonate-degrading strain Pseudaminobacter salicylatoxidans BN12, which oxidizes salicylate to 2-oxohepta-3,5-dienedioic acid by a ...
Ferraroni, M., Bürger, S., Briganti, F., Scozzafava, A., Matera, I., Stolz, A.   +5 more
core   +1 more source

nag Genes of Ralstonia (Formerly Pseudomonas ) sp. Strain U2 Encoding Enzymes for Gentisate Catabolism

, 2001
Ralstonia sp. strain U2 metabolizes naphthalene via gentisate to central metabolites. We have cloned and sequenced a 21.6-kb region spanning the nag genes. Upstream of the pathway genes are nagY,
Sergio L. Fuenmayor, Ning-Yi Zhou, Peter A. Williams   +2 more
core   +1 more source

Controlling the Redox Chemistry of Cobalt Radiopharmaceuticals

Angewandte Chemie, Volume 136, Issue 50, December 9, 2024.
The elementally matched 55Co (PET imaging)/58mCo (therapy) radioisotope pair is suitable for tandem diagnostic/therapeutic radiopharmaceuticals. Modulation of the Co2+/3+ redox couple is facile in mild oxidative conditions compatible with radiopharmaceutical synthesis, including radiolysis by the isotope's endogenous decay properties.
Wilson Lin, Dariusz Śmiłowicz, M. Andrey Joaqui‐Joaqui, Abhijit Bera, Zhuoran Zhong, Eduardo Aluicio‐Sarduy, Jason C. Mixdorf, Todd E. Barnhart, Jonathan W. Engle, Eszter Boros   +9 more
wiley   +2 more sources