ChnagG Plays the Role of 5-Salicylate Hydroxylase in the Gentisic Acid Pathway of Salicylic Acid Metabolism in Cochliobolus heterostrophus. [PDF]
The ChnagG gene in Cochliobolus heterostrophus encodes 5‐salicylate hydroxylase, converting salicylic acid (SA) to gentisic acid, enhancing pathogenicity and suppressing plant SA signalling‐mediated defences during infection. ABSTRACT Salicylic acid (SA) plays a crucial role in the defence strategies of plants against fungal pathogens.
Xu Y +6 more
europepmc +2 more sources
Bringing up to date the toolkit for the catabolism of aromatic compounds in fungi: The unexpected 1,2,3,5-tetrahydroxybenzene central pathway. [PDF]
Our understanding of how fungi utilize gallate or other syringyl derivatives is, to date, scarce and mostly relies on unproven assumptions. This study demonstrates the existence of a new 1,2,3,5‐tetrahydroxybenzene central pathway for the catabolism of gallate and related compounds in numerous fungi.
Martins TM +5 more
europepmc +2 more sources
Synergy effects in heavy metal Ion chelation with aryl- and aroyl-substituted thiourea derivatives [PDF]
Detection and removal of metal ion contaminants have attracted great interest due to the health risks that they represent for humans and wildlife. Among the proposed compounds developed for these purposes, thiourea derivatives have been shown as quite ...
Aguilar-Galindo, Fernando +4 more
core +1 more source
Influence of metal ions on bioremediation activity of protocatechuate 3,4-dioxygenase from KB2 [PDF]
The aim of this paper was to describe the effect of various metal ions on the activity of protocatechuate 3,4- dioxygenase from Stenotrophomonas maltophilia KB2.
Guzik, Urszula +3 more
core +4 more sources
Gentisate pathway in Salmonella typhimurium: metabolism of m-hydroxybenzoate and gentisate [PDF]
Salmonella typhimurium was shown to use the gentisate pathway to metabolize m-hydroxybenzoate and gentisate, m-Hydroxybenzoate hydroxylase and gentisate 1,2-dioxygenase were induced by growth on either gentisate or m-hydroxybenzoate. These enzymes were not detected when the bacteria were grown with glucose or glucose and either m-hydroxybenzoate or ...
F E, Goetz, L J, Harmuth
openaire +2 more sources
Theophylline–gentisic acid (1/1) [PDF]
In the title 1:1 cocrystal, C(7)H(8)N(4)O(2)·C(7)H(6)O(4), the anti-asthmatic drug theophylline (systematic name: 1,3-dimethyl-7H-purine-2,6-dione) and a non-steroidal anti-inflammatory drug, gentisic acid (systematic name: 2,5-dihydroxy-benzoic acid) crystallize together, forming two-dimensional hydrogen-bonded sheets involving N-H⋯O and O-H⋯N ...
Aitipamula, S., Chow, P.S., Tan, R.B.H.
openaire +2 more sources
Expanding Antarctic biogeography: microbial ecology of Antarctic island soils
The majority of islands surrounding the Antarctic continent are poorly characterized in terms of microbial macroecology due to their remote locations, geographical isolation and access difficulties. The 2016/2017 Antarctic Circumnavigation Expedition (ACE) provided unprecedented access to a number of these islands.
Pedro H. Lebre +14 more
wiley +1 more source
The crystal structure of the monocupin 5‐nitrosalicylate 1,2‐dioxygenase, an iron(II)‐dependent ring‐cleaving dioxygenase, from Bradyrhizobium sp. was determined by molecular replacement using a theoretical model obtained by AlphaFold2. Comparison with structures of other members of the same class and docking of the substrate allowed identification of ...
Erik Eppinger +2 more
wiley +1 more source
Structural, Spectroscopic, and Electrochemical Properties of Nonheme Fe(II)-Hydroquinonate Complexes: Synthetic Models of Hydroquinone Dioxygenases [PDF]
Using the tris(3,5-diphenylpyrazol-1-yl)borate (Ph2Tp) supporting ligand, a series of mono- and dinuclear ferrous complexes containing hydroquinonate (HQate) ligands have been prepared and structurally characterized with X-ray crystallography.
Baum, Amanda E. +4 more
core +2 more sources
Emerging roles for thiol dioxygenases as oxygen sensors
Thiol dioxygenases (TDOs) catalyse oxidation of thiols to sulphinates. Recent reports identify TDOs which catalyse oxidation of N‐terminal cysteine residues of protein substrates in an O2‐sensitive manner, promoting degradation: N‐terminal cysteinyl dioxygenases (NCOs). These appear to form a separate subclass of TDO from those which catalyse oxidation
Dona M. Gunawardana +2 more
wiley +1 more source

