Results 31 to 40 of about 258 (154)
Efficient synthesis of morphine and codeine [PDF]
, 2010 The present invention relates to methods for the synthesis of morphine, intermediates, salts and derivatives thereof. In preferred embodiments, the invention relates to methods for improving the efficiency and overall yield of said morphine, morphine ...
Fauber, Benjamin P. +2 more
core +2 more sources
Redirecting a Fungal Quercetin 2,3‐Dioxygenase Toward Artificial Flavonols
ChemCatChem, Volume 18, Issue 6, 27 March 2026.A novel quercetin 2,3‐dioxygenase was engineered to reshape its substrate‐binding cavity and redirect its specificity toward artificial flavonols. One variant with a larger substrate‐binding cavity exhibited 20‐ to 1750‐fold higher activity toward bulky flavonols with phenyl‐based substitutions at position C‐8.
Michael Kotik +9 more
wiley +1 more source
Molecular Nutrition &Food Research, Volume 69, Issue 23, December 2025.This cross‐over feeding trial identified 65 plasma and urine metabolites distinguishing a Healthy from a Typical Australian Diet. A composite metabolite score was linked to improved cardiometabolic markers. Results highlight distinct short‐term metabolomic signatures of diet quality, offering a promising tool for objective dietary assessment pending ...
Jordan Stanford +6 more
wiley +1 more source
Environmental Microbiology Reports, Volume 17, Issue 5, October 2025.Cold‐adapted Rhodococcus sp. strain R1B_2T from Arctic Tupirvik Beach (Northwest Passage) degrades short‐ to long‐chain hydrocarbons in summer seawater (−1°C to 5°C) via a synergistic activity of key hydrocarbon degradation genes (alkB, CYP153, almA, and ladA), with rhlABCR‐linked rhamnolipid production supporting biodegradation.
Nastasia J. Freyria +4 more
wiley +1 more source
Health Science Reports, Volume 8, Issue 9, September 2025.ABSTRACT Background and Aims Previous studies have shown that gut microbiota is associated with bladder cancer. However, the causal relationships and potential mediating factors between the gut microbiota (GM) and bladder cancer (BCa) have not been well defined.
Kai Che, Dong Qian, Shuxia Cui, Fei Xie
wiley +1 more source
Microbial Biotechnology, Volume 18, Issue 9, September 2025.Several strategies for biotransformation are compared and a comprehensive analytical characterisation of the novel dihydrodiol is given. ABSTRACT Bacterial Rieske non‐heme iron oxygenases catalyse the transformation of a wide range of aromatic compounds to vicinal cis‐dihydrodiols.
Martina Kiel +3 more
wiley +1 more source
Aging Cell, Volume 24, Issue 3, March 2025.The study identified dysregulated fatty acid metabolism and inflammation as contributors to physio‐cognitive decline syndrome (PCDS). Sex‐specific metabolic disruptions were noted, with altered central carbon and tyrosine metabolism more pronounced in men and glutathione pathway perturbations more evident in women.
Yi‐Long Huang +7 more
wiley +1 more source
Functional genomics and proteomic analysis of gentisate degradation in Pseudomonas alcaligenes NC1MB 9867 [PDF]
, 2007 Ph.DDOCTOR OF ...
ZHAO BING
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Use of fluorinated derivatives of 4-aminopyridine in therapeutics and medical imaging [PDF]
, 2023 The present disclosure provides novel compounds, including compounds that bind to potassium channels, methods for their manufacture, and methods for their use, including their use to diagnose and/or assess traumatic brain injury and use to treat ...
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Methods and compositions using ADAM10 inhibitors to treat bacterial infections [PDF]
, 2023 Certain embodiments are directed to compositions and methods of inhibiting a pathogenic bacterial infection involving ADAM10, specifically a method for treating pore-forming toxin-inducted pathology caused by exposure to staphylococcus in a subject ...
core