Results 21 to 30 of about 258 (154)

A structurally unique Fusobacterium nucleatum tannase provides detoxicant activity against gallotannins and pathogen resistance

Microbial Biotechnology, Volume 15, Issue 2, Page 648-667, February 2022., 2022
A new tannase enzyme from the cancer‐related pathogen Fusobacterium nucleatum is important for the survival of the bacteria under the stress conditions derived from the presence of dietary gallotannins. Using structural studies and molecular modelling we describe new structural features for this enzyme.
José Miguel Mancheño, Estíbaliz Atondo, Julen Tomás‐Cortázar, José Luís Lavín, Laura Plaza‐Vinuesa, Itziar Martín‐Ruiz, Diego Barriales, Ainhoa Palacios, Claudio Daniel Navo, Leticia Sampedro, Ainize Peña‐Cearra, Miguel Ángel Pascual‐Itoiz, Janire Castelo, Ana Carreras‐González, Donatello Castellana, Aize Pellón, Susana Delgado, Patricia Ruas‐Madiedo, Blanca de las Rivas, Leticia Abecia, Rosario Muñoz, Gonzalo Jiménez‐Osés, Juan Anguita, Héctor Rodríguez   +23 more
wiley   +1 more source

The ß‐ketoadipate pathway of Acinetobacter baumannii is involved in complement resistance and affects resistance against aromatic antibiotics

Environmental Microbiology Reports, Volume 14, Issue 1, Page 170-178, February 2022., 2022
Summary Acinetobacter baumannii can thrive on a broad range of substrates such as sugars, alcohols, lipids, amino acids and aromatic compounds. The latter three are abundant in the human host and are potential candidates as carbon sources for the metabolic adaptation of A. baumannii to the human host.
Jennifer Breisch, Lisa Sophie Huber, Peter Kraiczy, Josephine Hubloher, Beate Averhoff   +4 more
wiley   +1 more source

PahT regulates carbon fluxes in Novosphingobium sp. HR1a and influences its survival in soil and rhizospheres

Environmental Microbiology, Volume 23, Issue 6, Page 2969-2991, June 2021., 2021
Summary Novosphingobium sp. HR1a is a good biodegrader of PAHs and aromatic compounds, and also a good colonizer of rhizospheric environments. It was previously demonstrated that this microbe is able to co‐metabolize nutrients existing in root exudates together with the PAHs.
Ana Segura, Zulema Udaondo, Lázaro Molina   +2 more
wiley   +1 more source

Microbial transformation of xenobiotics for environmental bioremediation [PDF]

, 2011
The accumulation of recalcitrant xenobiotic compounds is due to continuous efflux from population and industrial inputs that have created a serious impact on the pristine nature of our environment. Apart from this, these compounds are mostly carcinogenic,
Bandyopadhyay, D, Chanda, P, Chatterjee, S, Chattopadhyay, P, Das, K, Pan, I, Sen, SK, Sinha, S   +7 more
core   +2 more sources

Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation. [PDF]

, 2013
3-Hydroxybenzoate 6-hydroxylase (3HB6H) from Rhodococcus jostii RHA1 is a dimeric flavoprotein that catalyzes the NADH- and oxygen-dependent para-hydroxylation of 3-hydroxybenzoate to 2,5-dihydroxybenzoate.
Barendregt A, MATTEVI, ANDREA, Montersino S, ORRU', ROBERTO, van Berkel WJ, van Duijn E, Westphal AH   +6 more
core   +1 more source

Gentisic acid and its 3- and 4-methyl-substituted homologues as intermediates in the bacterial degradation of m-cresol, 3,5-xylenol and 2,5-xylenol [PDF]

, 1971
1. Intact cells of a non-fluorescent Pseudomonas grown with m-cresol, 2,5-xylenol, 3,5-xylenol, 3-ethyl-5-methylphenol or 2,3,5-trimethylphenol rapidly oxidized all these phenols to completion. 3-Hydroxybenzoate and 2,5-dihydroxybenzoate (gentisate) were
D. J. Hopper, P. J. Chapman
core   +1 more source

Delftia sp LCW, a strain isolated from a constructed wetland shows novel properties for dimethylphenol isomers degradation [PDF]

, 2018
BACKGROUND: Dimethylphenols (DMP) are toxic compounds with high environmental mobility in water and one of the main constituents of effluents from petro- and carbochemical industry.
Harms, Hauke, Heipieper, Hermann J., Jehmlich, Nico, Junca, Howard, Martinez-Lavanchy, Paula M., Pieper, Dietmar H., Rincon, Carlos A., Vásquez-Piñeros, Mónica A.   +7 more
core   +1 more source

Controlling the Redox Chemistry of Cobalt Radiopharmaceuticals

Angewandte Chemie, Volume 136, Issue 50, December 9, 2024.
The elementally matched 55Co (PET imaging)/58mCo (therapy) radioisotope pair is suitable for tandem diagnostic/therapeutic radiopharmaceuticals. Modulation of the Co2+/3+ redox couple is facile in mild oxidative conditions compatible with radiopharmaceutical synthesis, including radiolysis by the isotope's endogenous decay properties.
Wilson Lin, Dariusz Śmiłowicz, M. Andrey Joaqui‐Joaqui, Abhijit Bera, Zhuoran Zhong, Eduardo Aluicio‐Sarduy, Jason C. Mixdorf, Todd E. Barnhart, Jonathan W. Engle, Eszter Boros   +9 more
wiley   +2 more sources

Cross-conjugated 2,5-cyclohexadienone and related synthesis methods [PDF]

, 2010
The present invention relates to methods for the synthesis of galanthamine, morphine, intermediates, salts and derivatives thereof. In preferred embodiments, the invention relates to methods for improving the efficiency and overall yield of said morphine,
Benjamin P. Fauber, Neeraj Sane, Philip D. Magnus   +2 more
core   +1 more source

Decoding Regioselective Reaction Mechanism of the Gentisic Acid Catalyzed by Gentisate 1,2-Dioxygenase Enzyme

, 2022
Gentisate 1,2-dioxygenase (GDO), a ring-fission non-heme dioxygenase enzyme, displays a unique regioselective reaction of gentisic acid (GTQ) in the presence of molecular oxygen. GTQ is an important intermediate in the aerobic biodegradation pathways of recalcitrant polyaromatic hydrocarbons (PAHs) pollutants.
Rounak Nath, Rabindranath Manna, Ankan Paul   +2 more
openaire   +1 more source