Results 51 to 60 of about 363,358 (296)

An integrated prognostic model of nuclear-encoded mitochondrial gene signature and clinical information for hepatocellular carcinoma

Shanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To establish a prognostic model for the overall survival (OS) of hepatocellular carcinoma (HCC) based on mitochondrial genes and clinical information.Methods·The gene expression and the clinical data of 369 HCC patients and 50 controls with ...
Kedeerya Aishanjiang, FU Yi, LAI Donglin, WU Hailong, GONG Wei   +4 more
doaj   +1 more source

Geo-spatial mapping of Carbon Dioxide and Carbon Monoxide within the University of Lagos, Nigeria [PDF]

, 2023
Musa B. Animashaun, Alfred Sunday Alademomi, Chukwuma Okolie, Oluwatimileyin Abolaji, Babatunde Ojegbile, Olagoke E. Daramola, Nehemiah Sabinus Alozie, Abdulwaheed Tella   +7 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

The Role of Quality in the Adjudication of Public Tenders [PDF]

Potchefstroom Electronic Law Journal, 2014
The quality of the goods or services that government procures is obviously a very important consideration in deciding which supplier should be awarded a particular public tender.
Geo Quinot
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

HOTAIR Facilitates Endocrine Resistance in Breast Cancer Through ESR1/miR-130b-3p Axis: Comprehensive Analysis of mRNA-miRNA-lncRNA Network

International Journal of General Medicine, 2021
Mingdi Zhang, Kejin Wu, Peng Zhang, Yiran Qiu, Fang Bai, Hongliang Chen Department of Breast Surgery, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, People’s Republic of ChinaCorrespondence: Hongliang ChenDepartment of Breast Surgery ...
Zhang M, Wu K, Zhang P, Qiu Y, Bai F, Chen H   +5 more
doaj  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Identification of MiR-223 Associated with Diagnosis in Ectopic Pregnancy

International Journal of General Medicine, 2023
Jiahan Qiu,1,2 Jiaxun Chen,2 Gaopi Deng,1,* Shuo Yuan1,* 1Department of Gynaecology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China; 2First Clinical Medical School, Guangzhou ...
Qiu J, Chen J, Deng G, Yuan S
doaj  

Geografía e inteligencia territorial : Geo-grafein, Geo-explanans, Geo-transformare [PDF]

, 2013
La Geografía y la Inteligencia Territorial pueden, juntas, ser una puerta a disciplinas y proyectos científicos mas encantadores, alegres y útiles en miles de millones de personas que no hacen Geografía, y que la conocen de otra forma, cuando no más crítica, más tradicional.
openaire   +3 more sources