Results 41 to 50 of about 10,323 (260)

Optimality conditions and Lagrange multipliers for shape and topology optimization problems

Atti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali, 2023
We discuss first order optimality conditions for geometric optimization problems with Neumann boundary conditions and boundary observation. The methods we develop here are applicable to large classes of state systems or cost functionals.
Dan Tiba
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Equivalence Class Characterizations of Near Fixed Points and Interval Ellipses in Coupled Metric and G-Metric Spaces With Applications

Journal of Mathematics
In this paper, we suggest a rigorous equivalence class description of interval ellipses and near fixed points in coupled metric and G-metric spaces with applications. In both metric and G-metric frameworks, we prove that the equivalence classes formed by
G. Sudhaamsh Mohan Reddy, Mohammad Sajid, Ali Allahem   +2 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

On equivalency of various geometric structures [PDF]

Journal of Geometry, 2013
The paper contains 27 pages, 3 tables and 2 tree ...
Shaikh, Absos Ali, Kundu, Haradhan
openaire   +2 more sources

Minisuperspace cosmology in extended geometric trinity of gravity

European Physical Journal C: Particles and Fields
We investigate Extended Geometric Trinity of Gravity at both classical and quantum cosmological levels using the minisuperspace approach. Adopting Noether symmetries to select viable models, we examine metric-affine theories of gravity, in particular the
Emmanuele Battista, Salvatore Capozziello, Stefano Pastore   +2 more
doaj   +1 more source

Experimental analysis of swirl number and nozzle design for scale-up of partially cracked ammonia flames

Applications in Energy and Combustion Science
Due to its ease of storage and existing global distribution network, interest in the use of renewably produced ammonia for decarbonising energy systems is growing.
Jordan Davies, Daisuke Sato, Syed Mashruk, Agustin Valera-Medina   +3 more
doaj   +1 more source