Results 51 to 60 of about 10,323 (260)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

geometrical equivalence

, 2014
Citation: 'geometrical equivalence' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.G02618 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Complexity measures from geometric actions onVirasoro and Kac-Moody orbits

Journal of High Energy Physics, 2020
We further advance the study of the notion of computational complexity for 2d CFTs based on a gate set built out of conformal symmetry transformations.
Johanna Erdmenger, Marius Gerbershagen, Anna-Lena Weigel   +2 more
doaj   +1 more source

A phase III, randomised, double‐blind, multi‐national clinical trial comparing SB12 (proposed eculizumab biosimilar) and reference eculizumab in patients with paroxysmal nocturnal haemoglobinuria

eJHaem, 2023
Treatment of paroxysmal nocturnal haemoglobinuria (PNH) includes the monoclonal antibody eculizumab. This randomised, double‐blind, multi‐national cross‐over Phase III study in PNH patients aimed to demonstrate the equivalence of the proposed eculizumab ...
Jun Ho Jang, Roberta Demichelis Gomez, Horia Bumbea, Larysa Nogaieva, Lily Lee Lee Wong, Soo Min Lim, Younsoo Kim, Jihye Park   +7 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

GRADED MORITA EQUIVALENCES FOR GEOMETRIC AS-REGULAR ALGEBRAS [PDF]

Glasgow Mathematical Journal, 2012
AbstractClassification of AS-regular algebras is one of the major projects in non-commutative algebraic geometry. In this paper, we will study when given AS-regular algebras are graded Morita equivalent. In particular, for every geometric AS-regular algebra A, we define another graded algebra A, and show that if two geometric AS-regular algebras A and ...
Mori, Izuru, Ueyama, Kenta
openaire   +2 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Closed equivalence relations on compact spaces and pairs of commutative C*-algebras: a Categorical Approach

Visnik Harkivsʹkogo Nacionalʹnogo Universitetu im. V.N. Karazina. Cepiâ Matematika, Prikladna Matematika i Mehanika
In this paper, we study a categorical extension of the classical Gelfand-Naimark duality between compact Hausdorff spaces and commutative unital C*-algebras.
Роман Скуріхін, Сергій Гефтер, Євген Каролінський   +2 more
doaj   +1 more source

Rough Neutrosophic Multisets Geometric Aggregation Operator with Entropy Weight Combined Roughness Dice Similarity Measure and Its Application [PDF]

ITM Web of Conferences
Rough neutrosophic multisets (RNM) is an uncertainty set theory generalized from the rough neutrosophic set. In the same equivalence relation, the universal set is a neutrosophic multisets with boundary regions involving lower and upper approximation. To
Alias Suriana, Mohamad Daud, Shuib Adibah, Mustapha Norzieha, Md Yasin Roliza, Mohd Yusoff Nazhatul Sahima, Broumi Said   +6 more
doaj   +1 more source

TROIKA‐1: A double‐blind, randomized, parallel group, study aimed to demonstrate the equivalent pharmacokinetic profile of HD201, a potential biosimilar candidate to trastuzumab, versus EU‐Herceptin® and US‐Herceptin® in healthy male subjects

Pharmacology Research & Perspectives, 2021
Prestige Biopharma Ltd (Singapore) has developed HD201, a proposed biosimilar to reference product trastuzumab. As a part of the stepwise approach to ensure comparability between the biosimilar candidate and the reference medicinal product, a phase I ...
Martin Demarchi, Pierre Coliat, Kristi Mclendon, Jocelyn Chung Shii Hii, Peggy Feyaerts, Felicia Ang, Litha Jaison, Filip Deforce, Marie Paule Derde, Michael Jinwoo Kim, Lisa Soyeon Park, Alexandre Detappe, Xavier Pivot   +12 more
doaj   +1 more source