Results 41 to 50 of about 686,345 (230)

Software framework for intrinsic curve interpolation in the 4D hypersphere using stereographic projection

SoftwareX
We present a symbolic and geometric software framework, implemented in Mathematica, for constructing and interpolating curves intrinsically embedded in the four-dimensional hypersphere (S3⊂E4) using stereographic projection and its inverse. The framework
Vanessa H. Silupú-Ortega, Ricardo Velezmoro-León, Manuel H. García-Saba, Eder Escobar-Gómez, Robert Ipanaqué-Chero   +4 more
doaj   +1 more source

A geometrical approach for surface reconstruction by means of radial basis functions with compact support

Revista Facultad de Ingeniería Universidad de Antioquia, 2013
Recently in the community of computer vision related with the surface reconstruction processes of free-form objects there has been a growing trend in the use of interpolation techniques.
Germán Torres-Sánchez, John William Branch   +1 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

The morphing for continuous generalization of linear features based on Dynamic Time Warping distance

Geocarto International, 2023
Shape morphing has been used to generate arbitrary scale maps in the field of continuous generalization in recent years. The morphing approach consists of two main steps: shape characteristic matching and trajectory interpolation.
Jingzhong Li, Kainan Mao
doaj   +1 more source

Geodesic Learning With Uniform Interpolation on Data Manifold

IEEE Access, 2022
Recently with the development of deep learning on data representation and generation, how to sampling on a data manifold becomes a crucial problem for research.
Cong Geng, Jia Wang, Li Chen, Zhiyong Gao   +3 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Modeling exponential interpolation curves in point calculus

Омский научный вестник
In engineering geometry the problem of creating flexible curves incident to given points is relevant. The article describes a method for modeling interpolation curves in point calculus based on Bezier curves.
A. V. Stepura, E. V. Konopatskiy
doaj   +1 more source