Results 81 to 90 of about 4,312,747 (279)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Sharp bounds for a special quasi-arithmetic mean in terms of arithmetic and geometric means with two parameters

Journal of Inequalities and Applications, 2017
In the article, we present the best possible parameters λ = λ ( p ) $\lambda=\lambda (p)$ and μ = μ ( p ) $\mu=\mu(p)$ on the interval [ 0 , 1 / 2 ] $[0, 1/2]$ such that the double inequality G p [ λ a + ( 1 − λ ) b , λ b + ( 1 − λ ) a ] A 1 − p ( a , b )
Wei-Mao Qian, Yu-Ming Chu
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Two-Stage Classification with SIS Using a New Filter Ranking Method in High Throughput Data

Mathematics, 2019
Over the last decade, high dimensional data have been popularly paid attention to in bioinformatics. These data increase the likelihood of detecting the most promising novel information.
Sangjin Kim, Jong-Min Kim
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

F–Geometric Mean Graphs [PDF]

, 2015
In a study of traffic, the labelling problems in graph theory can be used by considering the crowd at every junction as the weights of a vertex and expected average traffic in each street as the weight of the corresponding edge. If we assume the expected
Baskar, A. D., Arockiaraj, S.
core   +1 more source

Sharp bounds for the tangent mean by weighted power mean of arithmetic and geometric means

Open Mathematics
Using the monotonicity rules for the ratios of two functions (power series), the optimal bounds for the tangent mean in terms of weighted power means of arithmetic and geometric means are obtained.
Xu Hui-Zuo
doaj   +1 more source

Weighted Geometric Mean (WGM) method: A new chromatic adaptation model. [PDF]

PLoS One, 2023
Shen C, Fairchild MD.
europepmc   +1 more source