Results 51 to 60 of about 76,166 (256)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Planar Geometric Projections and Viewing Transformations [PDF]

open access: yesACM Computing Surveys, 1978
In computer graphics one is often concerned with representing three-dimensional objects on a two-dimensional display surface. The choice of such a representation depends on several factors, including the purpose for which the representation is intended, the visual effects tha t are desired, and the shape of the object.
Ingrid Carlbom, Joseph Paciorek
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Modeling Transmission Lines With Open Boundaries via Infinite Mapping Layer

open access: yesIEEE Journal of Microwaves
In this paper we introduce the use of several different Infinite Mapping Layers to model open boundaries in the 2-D Finite Element Method for the computation of transmission line parameters.
Gines Garcia-Contreras   +5 more
doaj   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket   +14 more
wiley   +1 more source

Affine Geometrical Region CNN for Object Tracking

open access: yesIEEE Access, 2020
The state-of-the-art trackers using deep learning technology have little special strategy to gain the bounding box well when the target suffers drastic geometric deformation.
Yinghong Xie, Jie Shen, Chengdong Wu
doaj   +1 more source

Geometrical transformations and development of geometry

open access: yes, 2021
A way of systematizing different geometries by geometrical transformations is presented by using Klein’s perspective. Symmetry is considered the basic precedent, and different groups of transformations are introduced by using Erlangen program ideas.
Joaquin Giménez   +2 more
openaire   +2 more sources

Geometric hydrodynamics via Madelung transform [PDF]

open access: yesProceedings of the National Academy of Sciences, 2018
Significance Geometry has always played a fundamental role in theoretical physics via symmetries and conservation laws. We present a geometric framework revealing a closer link between hydrodynamics and quantum mechanics than previously recognized.
Boris Khesin   +2 more
openaire   +4 more sources

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