Results 31 to 40 of about 76,166 (256)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A general geometric transformation model for line-scan image registration

EURASIP Journal on Advances in Signal Processing, 2023
A reasonable geometric transformation model is the key to image registration. When the relative motion direction between the line-scan camera and the object is strictly parallel to the planar object, it is possible to align the image by using the eight ...
Lei Fang, Zelin Shi, Yunpeng Liu, Chenxi Li, Mingqi Pang, Enbo Zhao   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Students’ Computational Thinking Difficulty Pathways in Geometric Transformation after GeoGebra-Assisted Problem-Based Learning

Inovasi Matematika
Computational thinking is an important mathematical process in problem solving that encompasses the abilities to analyze situations, develop strategies, recognize patterns, and design systematic procedures. Understanding students’ computational thinking
Ruth Helen Simarmata, Esterlina, Fifi Dhafia Az Zahra   +2 more
doaj   +3 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Geometric transformation and cultural values in traditional batik of Banyumas and Pekalongan: An ethnomathematics study

Jurnal Elemen
Banyumas and Pekalongan batik are local cultural heritages of Central Java that contain philosophical values, regional identity, and geometric patterns.
Kusno Kusno, Gunawan, Nalim, Eka Setyaningsih, Miftahul Furqon, Mohd Faiz   +5 more
doaj   +1 more source

A Learnable Joint Spatial and Spectral Transformation for High Resolution Remote Sensing Image Retrieval

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2021
Geometric and spectral distortions of remote sensing images are key obstacles for deep learning-based supervised classification and retrieval, which are worsened by cross-dataset applications. A learnable geometric transformation model imbedded in a deep
Yameng Wang, Shunping Ji, Yongjun Zhang
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source