Results 21 to 30 of about 3,161,902 (289)
Non-commutative geometry, dynamics, and infinity-adic Arakelov geometry [PDF]
, 2003 In Arakelov theory a completion of an arithmetic surface is achieved by enlarging the group of divisors by formal linear combinations of the ``closed fibers at infinity''.
Consani, Caterina, Marcolli, Matilde
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Geometry in the Transition from Primary to Post-Primary [PDF]
, 2014 This article is intended as a kind of precursor to the document Geometry for Post-primary School Mathematics, part of the Mathematics Syllabus for Junior Certicate issued by the Irish National Council for Curriculum and Assessment in the context of ...
Barry, Patrick D., O'Farrell, Anthony G.
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Fluctuating Commutative Geometry
, 2003 We use the framework of noncommutative geometry to define a discrete model for fluctuating geometry. Instead of considering ordinary geometry and its metric fluctuations, we consider generalized geometries where topology and dimension can also fluctuate.
de Albuquerque, Luiz C. +2 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Discrete space-time geometry and skeleton conception of particle dynamics
, 2011 It is shown that properties of a discrete space-time geometry distinguish from properties of the Riemannian space-time geometry. The discrete geometry is a physical geometry, which is described completely by the world function.
J.L. Synge +7 more
core +1 more source