Results 41 to 50 of about 932,040 (258)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Normal forms in Poisson geometry [PDF]
, 2013 The structure of Poisson manifolds is highly nontrivial even locally. The first important result in this direction is Conn's linearization theorem around fixed points. One of the main results of this thesis (Theorem 2) is a normal form theorem in Poisson
Sub Algebra,Geometry&Mathem. Logic begr. +2 more
core +1 more source
The geometry of learning [PDF]
Journal of Mathematical Psychology, 2018 We establish a correspondence between Pavlovian conditioning processes and fractals. The association strength at a training trial corresponds to a point in a disconnected set at a given iteration level. In this way, one can represent a training process as a hopping on a fractal set, instead of the traditional learning curve as a function of the trial ...
openaire +6 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Bookreview Geometry of algebraic curves. Volume II (Grundlehren der mathematischen Wissenschaften, 268) [PDF]
, 2012 Geometry of algebraic curves.
Sub Algebra,Geometry&Mathem. Logic begr. +2 more
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Zeta function rigidity : a view from noncommutative geometry [PDF]
, 2011 In this thesis we study the zeta function formalism of finitely summable spectral triples in noncommutative geometry introduced by Alain Connes in 1995.
de Jong, J.W.W. +2 more
core +1 more source
Ways of linking geometry and algebra, the case of Geogebra
, 2007 This paper discusses ways of enhancing the teaching of mathematics through enabling learners to gain stronger links between geometry and algebra. The vehicle for this is consideration of the affordances of GeoGebra, a form of freely-available open-source
BSRLM Geometry Working Group +2 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source