Results 51 to 60 of about 3,161,902 (289)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Geometry of rank tests [PDF]

open access: yes, 2006
We study partitions of the symmetric group which have desirable geometric properties. The statistical tests defined by such partitions involve counting all permutations in the equivalence classes. These permutations are the linear extensions of partially
Morton, Jason   +4 more
core   +3 more sources

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket   +14 more
wiley   +1 more source

Hamilton Geometry - Phase Space Geometry from Modified Dispersion Relations

open access: yes, 2018
Quantum gravity phenomenology suggests an effective modification of the general relativistic dispersion relation of freely falling point particles caused by an underlying theory of quantum gravity. Here we analyse the consequences of modifications of the
Barcaroli, Leonardo   +4 more
core   +1 more source

Script Geometry

open access: yes, 2016
In this paper we describe the foundation of a new kind of discrete geometry and calculus called Script Geometry. It allows to work with more general meshes than classic simplicial complexes. We provide the basic definitions as well as several examples, like the Klein bottle and the projective plane.
Cerejeiras, Paula   +3 more
openaire   +4 more sources

Weyl geometry [PDF]

open access: yesGeneral Relativity and Gravitation, 2018
We develop the properties of Weyl geometry, beginning with a review of the conformal properties of Riemannian spacetimes. Decomposition of the Riemann curvature into trace and traceless parts allows an easy proof that the Weyl curvature tensor is the conformally invariant part of the Riemann curvature, and shows the explicit change in the Ricci and ...
openaire   +5 more sources

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti   +19 more
wiley   +1 more source

On organizing principles of Discrete Differential Geometry. Geometry of spheres

open access: yes, 2006
Discrete differential geometry aims to develop discrete equivalents of the geometric notions and methods of classical differential geometry. In this survey we discuss the following two fundamental Discretization Principles: the transformation group ...
Bobenko, Alexander I., Suris, Yuri B.
core   +2 more sources

Hyperbolic Geometry [PDF]

open access: yes, 2013
The author considers the space of relativistic velocities in the Minkowski vector space \(\mathbb{R}^{1,n}\) as the unit ball \(B^n \subset \mathbb{R}^n \) with the non-commutative non-associative invertible binary operation \(\oplus\), defined by the relativistic addition of velocities.
openaire   +4 more sources

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