Results 101 to 110 of about 42,320 (308)

Evaluation of TanDEM-X DEMs on selected Brazilian sites: comparison with SRTM, ASTER GDEM and ALOS AW3D30

, 2018
A first assessment of the TanDEM-X DEMs over Brazilian territory is presented through a comparison with SRTM, ASTER GDEM and ALOS AW3D30 DEMs in seven study areas with distinct geomorphological contexts, vegetation coverage and land use.
Grohmann, Carlos H.
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Landholding and landscape in Ottoman Cyprus [PDF]

, 2010
In Ottoman Cyprus (1571–1878), social organization was based above all on the ownership and exploitation of agricultural land. The social relations, economic processes and daily practices of landowning elites and peasant farmers alike were structured by ...
Given, M., Hadjianastasis, M.
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Three hundred thousand years of multi-millennial hydroclimate variability in Northern Africa based on speleothem records from Tunisia

Communications Earth & Environment
Hydroclimate changes in Northern Africa reflect the interplay between mid-latitude westerlies and the West African monsoon, along with their intensity variations.
Yun-Chuan Chung, Hatem Dhaouadi, Gianluca Marino, Emna Sbei, Heikki Seppä, Anu Kaakinen, Mahjoor Ahmad Lone, Hédi Ben Ouezdou, Silvia Frisia, Chuan-Chou Shen   +9 more
doaj   +1 more source

Дунд масштабын геоморфологийн зураг боловсруулах аргазүйн асуудалд

Proceedings of the Mongolian Academy of Sciences, 2017
In order to classify morphology and morphogenetic features of Mongolian eastern region, it is based on the field study measurements, high accurate digital elevation model (DEM), large scale topographical map and targeted to use mapping methodology on ...
Баянжаргал Б, Нямхүү М
doaj   +1 more source

Determinations of the slope fragmentation in the High Bieszczady Mountains [PDF]

, 2012
The determinations of the slope fragmentation in the High Bieszczady Mountains (Eastern Carpathians) are described basing on analysis of three chosen slopes: SW slopes of Mt. Bukowe Berdo, SW slopes of Polonina Carynska, NE slopes of Mt. Dział.
Bernatek-Jakiel, Anita
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Evidence of Titan's Climate History from Evaporite Distribution

, 2014
Water-ice-poor, 5-$\mu$m-bright material on Saturn's moon Titan has previously been geomorphologically identified as evaporitic. Here we present a global distribution of the occurrences of the 5-$\mu$m-bright spectral unit, identified with Cassini's ...
Baines, Kevin H., Barnes, Jason W., Buratti, Bonnie J., Clark, Roger N., MacKenzie, Shannon M., McCord, Thomas B., Mouélic, Stéphane Le, Nicholson, Phillip D., Rodriguez, Sebastien, Soderblom, Jason M., Sotin, Christophe   +10 more
core   +2 more sources