Results 101 to 110 of about 42,080 (309)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Monitoring sediment transfer processes on the desert margin [PDF]

LANDSAT Thematic Mapper and Multispectral Scanner data have been used to construct change detection images for three playas in south-central Tunisia. Change detection images have been used to analyze changes in surface reflectance and absorption between ...
Arwyn, R. Jones, Millington, Andrew C., Quarmby, Neil, Townshend, John R. G.   +3 more
core   +1 more source

Fluvial dynamics and watermills location in Basilicata (Southern Italy) [PDF]

, 2016
Watermills (grain mills, waulk mills, olive mills, sawmills and threshing machines) operated in the Basilicata Region from the Roman Period until the early decades of the twentieth century, representing an important feature of waterways that is today ...
Bishop, P., DEL MONTE, Maurizio, Grano, MARIA CARMELA, Lazzari, M.   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Дунд масштабын геоморфологийн зураг боловсруулах аргазүйн асуудалд

Proceedings of the Mongolian Academy of Sciences, 2017
In order to classify morphology and morphogenetic features of Mongolian eastern region, it is based on the field study measurements, high accurate digital elevation model (DEM), large scale topographical map and targeted to use mapping methodology on ...
Баянжаргал Б, Нямхүү М
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Landholding and landscape in Ottoman Cyprus [PDF]

, 2010
In Ottoman Cyprus (1571–1878), social organization was based above all on the ownership and exploitation of agricultural land. The social relations, economic processes and daily practices of landowning elites and peasant farmers alike were structured by ...
Given, M., Hadjianastasis, M.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Geomorphology of the Upper General River Basin, Costa Rica

Journal of Maps, 2019
In spite of the geomorphological diversity of Central America and Costa Rica, there are few detailed geomorphological maps. A 1:25,000 scale map of the Upper General River Basin (UGRB) in Costa Rica is presented, based on the interpretation of aerial ...
Adolfo Quesada-Román, José Juan Zamorano-Orozco   +1 more
doaj   +1 more source

Evidence of Titan's Climate History from Evaporite Distribution

, 2014
Water-ice-poor, 5-$\mu$m-bright material on Saturn's moon Titan has previously been geomorphologically identified as evaporitic. Here we present a global distribution of the occurrences of the 5-$\mu$m-bright spectral unit, identified with Cassini's ...
Baines, Kevin H., Barnes, Jason W., Buratti, Bonnie J., Clark, Roger N., MacKenzie, Shannon M., McCord, Thomas B., Mouélic, Stéphane Le, Nicholson, Phillip D., Rodriguez, Sebastien, Soderblom, Jason M., Sotin, Christophe   +10 more
core   +2 more sources