Results 41 to 50 of about 3,703 (157)

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

open access: yesCell Reports, 2018
Summary: Protein ubiquitination is a dynamic and reversible process of adding single ubiquitin molecules or various ubiquitin chains to target proteins. Here, using multidimensional omic data of 9,125 tumor samples across 33 cancer types from The Cancer ...
Zhongqi Ge   +740 more
doaj   +1 more source

‘There Has Been a Scandal’: Cultural Performers and the Strangers’ Churches of London

open access: yesRenaissance Studies, EarlyView.
ABSTRACT Despite what one might assume to have been a rigid line between London's refugee community—with its strict brand of Protestantism—and the city's performance cultures—often the target of strict Protestants' ire—historical records reveal a number of overlaps between those domains.
Matteo Pangallo
wiley   +1 more source

Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

open access: yesCell Reports, 2018
Summary: Hotspot mutations in splicing factor genes have been recently reported at high frequency in hematological malignancies, suggesting the importance of RNA splicing in cancer.
Michael Seiler   +733 more
doaj   +1 more source

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

open access: yesCell Reports, 2018
Summary: Gene fusions represent an important class of somatic alterations in cancer. We systematically investigated fusions in 9,624 tumors across 33 cancer types using multiple fusion calling tools.
Qingsong Gao   +746 more
doaj   +1 more source

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

open access: yesCell Reports, 2018
Summary: DNA damage repair (DDR) pathways modulate cancer risk, progression, and therapeutic response. We systematically analyzed somatic alterations to provide a comprehensive view of DDR deficiency across 33 cancer types.
Theo A. Knijnenburg   +762 more
doaj   +1 more source

Creating woodland through natural processes: Current understanding and knowledge gaps in Great Britain

open access: yesEcological Solutions and Evidence
Creating woodlands through natural processes, as opposed to traditional tree planting, is expected to result in more structurally diverse, locally adapted woodlands that enhance the resilience of existing treescapes.
Susannah Fleiss   +30 more
doaj   +1 more source

Systematic Analysis of Splice-Site-Creating Mutations in Cancer

open access: yesCell Reports, 2018
Summary: For the past decade, cancer genomic studies have focused on mutations leading to splice-site disruption, overlooking those having splice-creating potential. Here, we applied a bioinformatic tool, MiSplice, for the large-scale discovery of splice-
Reyka G. Jayasinghe   +750 more
doaj   +1 more source

Cowbirds use conspecific social information to detect host nests in the wild

open access: yesIbis, Volume 168, Issue 2, Page 799-804, April 2026.
Recent work shows that hosts of avian brood parasites use social information to increase egg rejection rates, but fewer studies explore how parasites themselves use such information to detect host nests in the wild. To determine whether wild Brown‐headed Cowbirds Molothrus ater use social information to detect host nests, we measured how individual ...
Omar J. Morosse   +2 more
wiley   +1 more source

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

open access: yesCell Reports, 2018
Summary: This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smoking and/or human papillomavirus (HPV). SCCs harbor 3q, 5p, and
Joshua D. Campbell   +784 more
doaj   +1 more source

Survival of a Long‐Lived Avian Scavenger: Implications of Age, Season, and Landscape Composition for Mortality Risk

open access: yesEcology and Evolution, Volume 16, Issue 3, March 2026.
The goal of this study was to evaluate survival and mortality risk in black vultures (Coragyps atratus), a protected native species of conflict management concern in the United States. High survival rates from this study help explain this species' population growth and range expansion and further inform allowable take for sustainable management ...
Spencer B. Hudson   +22 more
wiley   +1 more source

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