Results 31 to 40 of about 1,454 (181)

Calcitonin Gene-Related Peptide (CGRP)-Targeted Treatments—New Therapeutic Technologies for Migraine

open access: yesFuture Pharmacology, 2023
Migraine is ranked as the third most common disorder worldwide and is considered one of the most disabling neurological conditions. Its treatment has mostly relied on medications that were non-specifically developed for migraine, thus accompanied by low ...
Linda Sangalli, Stefania Brazzoli
doaj   +1 more source

Small-molecule CGRP receptor antagonists: A new approach to the acute and preventive treatment of migraine

open access: yesMedicine in Drug Discovery, 2020
Purpose: Current acute migraine treatment consists of migraine-specific agents, namely triptans, as well as non-specific analgesia, such as non-steroidal anti-inflammatory drugs and acetaminophen (paracetamol).
David Moreno-Ajona   +2 more
doaj   +1 more source

Emerging Pharmacological Treatments for Migraine in the Pediatric Population

open access: yesLife, 2022
Headaches in children and adolescents have high incidence and prevalence rates, with consequent elevated disability costs to individuals and the community. Pediatric migraine is a disorder with substantial clinical differences compared to the adult form.
Luigi Francesco Iannone   +2 more
doaj   +1 more source

Emerging drugs for the preventive treatment of migraine: a review of CGRP monoclonal antibodies and gepants trials

open access: yes, 2023
Introduction: Migraine is a leading cause of years lived with disability and preventive strategies represent a mainstay to reduce health-related disability and improve quality of life of migraine patients.
Tedeschi, Gioacchino   +13 more
core   +1 more source

Calcitonin gene-related peptide (CGRP) receptor antagonists for the acute treatment of migraines in adults

open access: yesDrugs in Context, 2022
Migraine headaches are widespread, debilitating and considered a main cause of disability worldwide. Symptoms of migraines include unilateral, pulsating pain that can last for hours to days, frequently associated with photophobia and phonophobia, nausea,
Eric R Ocheretyaner   +2 more
doaj   +1 more source

CGRP-Targeted Therapy in Vestibular Migraine-How Strong Is the Evidence? [PDF]

open access: yesEur J Neurol
open access articleBackground: Medications for migraine prevention targeting the calcitonin gene-related peptide (CGRP) pathway have substantially reduced symptom burden in many patients who have failed previous treatment strategies. In contrast, data on
Tarnutzer AA, Castro Abarca P, Kaski D.
europepmc   +2 more sources

sj-pdf-6-cep-10.1177_03331024231152169 - Supplemental material for Safety and tolerability of monoclonal antibodies targeting the CGRP pathway and gepants in migraine prevention: A systematic review and network meta-analysis

open access: yes, 2023
Supplemental material, sj-pdf-6-cep-10.1177_03331024231152169 for Safety and tolerability of monoclonal antibodies targeting the CGRP pathway and gepants in migraine prevention: A systematic review and network meta-analysis by Roberta Messina, Eva-Maria ...
Eva-Maria Huessler (14617393)   +5 more
core   +1 more source

sj-jpg-3-cep-10.1177_03331024231152169 - Supplemental material for Safety and tolerability of monoclonal antibodies targeting the CGRP pathway and gepants in migraine prevention: A systematic review and network meta-analysis

open access: yes, 2023
Supplemental material, sj-jpg-3-cep-10.1177_03331024231152169 for Safety and tolerability of monoclonal antibodies targeting the CGRP pathway and gepants in migraine prevention: A systematic review and network meta-analysis by Roberta Messina, Eva-Maria ...
Eva-Maria Huessler (14617393)   +5 more
core   +1 more source

New Approaches to Shifting the Migraine Treatment Paradigm

open access: yesFrontiers in Pain Research, 2022
The standard of care paradigm for migraine treatment has been based almost exclusively on approaches that grew out of the happenstance use of market pharmaceuticals.
Brian Johnson, Frederick G. Freitag
doaj   +1 more source

Future prophylactic treatments in migraine:Beyond anti-CGRP monoclonal antibodies and gepants

open access: yes, 2021
Migraine is ranked as a leading cause of years lived with disability among all neurological disorders. Therapies targeting the calcitonin gene-related peptide (CGRP) signaling pathway, including monoclonal antibodies against the receptor or ligand and ...
Do, T. P.   +5 more
core   +1 more source

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