Results 291 to 300 of about 375,661 (389)

Brown Tumors Mimicking Skeletal Metastases: A Diagnostic Pitfall in Primary Hyperparathyroidism

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Brown tumors are rare but important manifestations of primary hyperparathyroidism (PHPT). These benign, fibrotic, and erosive bony lesions result from localized rapid osteoclastic activity driven by excessive parathyroid hormone levels. Although brown tumors are considered one of the most pathognomonic signs of PHPT, they are infrequently ...
Uzma Akbar   +7 more
wiley   +1 more source

Immunotherapy‐Related Gastritis in Small Cell Lung Cancer Treatment With Durvalumab—A Case Report

open access: yesCancer Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background Durvalumab is a PD‐L1 inhibitor that triggers a blockade resulting in enhanced anti‐tumor responses related to increased T‐cell activation. There is potential for numerous immune‐related adverse events (irAEs) with this treatment, most of which have been shown to be effectively managed with high‐dose steroids.
Marc C. Cavaliere   +2 more
wiley   +1 more source

Impact of epicardial adipose tissue on myocardial function and structure in patients with severe aortic valve stenosis

open access: yesESC Heart Failure, Volume 12, Issue 6, Page 4230-4241, December 2025.
Epicardial adipose tissue (EAT) has been linked to adverse remodelling and outcomes in aortic valve stenosis (AS), yet mechanisms remain unclear. In 137 patients with severe AS undergoing CMR before TAVR, higher EAT (≥46.5 ml/m2) was associated with impaired left atrial (LA) reservoir strain, while ventricular morphology, function and tissue ...
Judith Gronwald   +10 more
wiley   +1 more source

Exercise‐induced out‐of‐proportion increase in afterload and impaired right ventricular contractile reserve in HFpEF

open access: yesESC Heart Failure, Volume 12, Issue 6, Page 4391-4400, December 2025.
Non‐cardiac dyspnoea (n = 34, NCD) and heart failure with preserved ejection fraction (n = 34, HFpEF) patients were classified according to right heart catheterisation. Cardiovascular magnetic resonance derived right ventricular (RV) haemodynamic indices for afterload (Ea), contractility (Ees) and RV/pulmonary artery coupling (Ea/Ees) were evaluated ...
Jan Sebastian Wolter   +11 more
wiley   +1 more source

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