Results 21 to 30 of about 224,238 (268)

Naturalistic study of “Adherence to Follow-Up” in the initial 1st year cohort of patients utilizing a tertiary hospital-based geriatric mental health-care service using the “Service Evaluation Framework”

Indian Journal of Social Psychiatry, 2022
Background: There are very few specialised hospital with quality assurance services catering to the needs of the elderly with mental illness. The concept of 'Appointment adherence' has received little attention in the field of geriatric mental health ...
Nitin Gupta, Subhash Das, Tanupreet Kaur
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Chronic Pruritus in Geriatric Patients: Prevalence, Associated Factors, and Itch-related Quality of Life

Acta Dermato-Venereologica
Chronic pruritus is a common condition that significantly impacts quality of life. However, data on chronic pruritus in geriatric populations remain limited.
Marlene Günther, Charlotte Kobus, Caroline Perner, Aline Schönenberg, Tino Prell   +4 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Macroscopic Features of the Intugementary System of Geriatric Kintamani Dogs

Media Kedokteran Hewan
Observing the health of Kintamani dogs, especially at geriatric age, is important as an effort to preserve their lives. Observations of the integumentary system can provide information related to clinical animal health.
Ni Putu Anggita Indrayani, I Nengah Wandia, I Wayan Nico Fajar Gunawan, Putu Devi Jayanti   +3 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Applying Beers Criteria for elderly patients to assess rational drug use at a university hospital in Northern Cyprus

Journal of Pharmacy and Bioallied Sciences, 2019
Background: Several regulations for potentially inappropriate medications (PIMs) have been published specifically for elderly patients to rationalize drug use in such vulnerable communities.
Sarah Khamis, Abdikarim Mohamed Abdi, Ali Uzan, Bilgen Basgut   +3 more
doaj   +1 more source

Hearing loss among the elderly at a geriatric centre in South-west Nigeria

Nigerian Journal of Medicine, 2023
Background: Aging is an unavoidable process that is connected with several health issues, including presbycusis, a degenerative disease of the cochlear hair cells and central auditory pathways with a resultant reduction in hearing acuity.
Samuel Okoh Sule, Ayotunde James Fasunla, Onyekwere George Benjamin Nwaorgu   +2 more
doaj   +1 more source