Results 131 to 140 of about 23,382 (287)

Guideline of guidelines: pelvic lymph node dissection at time of radical prostatectomy

open access: yesBJU International, EarlyView.
Objective To provide a comprehensive review, analysis and critique of guidelines from various oncological and urological organisations regarding the use pelvic lymph node dissection (PLND) in men undergoing radical prostatectomy (RP) for primary treatment of prostate cancer (PCa).
Jonathon Carll   +8 more
wiley   +1 more source

Are Cochlear Implants Indicated in the Advanced Aging Population?

open access: yes
The Laryngoscope, EarlyView.
India Jackson   +2 more
wiley   +1 more source

Identification, reliability, and validity of drug–drug interaction checkers in chronic diseases: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Drug–drug interactions (DDIs) pose major risks in chronic disease management where polypharmacy is common. Although digital DDI tools are used widely to aid healthcare professionals, tools rely on theoretical interactions. This limitation questions their reliability and validity for clinical relevancy.
Brayden Ng Gibson   +12 more
wiley   +1 more source

Preoperative geriatric assessment and follow-up of patients older than 75 years undergoing elective surgery for suspected colorectal cancer

open access: yes, 2019
Objectives: We investigated the predictive value of specific tools used in a Comprehensive Geriatric Assessment (CGA) with regard to postoperative outcome in patients 75 years and older undergoing elective colorectal cancer (CRC) surgery.
Lökk, Johan,   +4 more
core   +1 more source

Atezolizumab + Chemotherapy in Older Patients With Lung Cancer in Japan

open access: yesCancer Science, EarlyView.
OS (A–D) and PFS (E–H) in patients receiving (A/E) Atezo + CnP, (B/F) Atezo + PP, (C/G) Atezo + bev + CP, and (D/H) Atezo + CEa by age (≥ 70 years and < 70 years). aSaito R, et al. Presented at the 2024 American Society of Clinical Oncology Annual Meeting. Abstract 8092. Adapted with permission by the author.
Junichi Shimizu   +19 more
wiley   +1 more source

Geriatric oncology: Looking into grey scales

open access: yesCancer Research, Statistics, and Treatment, 2023
Rahul Ravind
doaj   +1 more source

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

open access: yesCancer Science, EarlyView.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo   +6 more
wiley   +1 more source

Mediating Effect of Depression on Relationship Between Sleep Disturbance and Locomotive Syndrome in Geriatric Cancer Patients

open access: yesJournal of Multidisciplinary Healthcare
Yao Chen,1,&ast; Hu-Nan Wang,2,3,&ast; Ying Chen,1 Xue-Fen Liang,4 Hai-Wa Xu,4 Rui-Rong Wu,1 Li-Hua Dong,4 Hui Su,1 Yu-Ling Yang1 1Department of Oncology, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu Province, 214122, People’s ...
Chen Y   +8 more
doaj  

Lactate Accelerates Early Angiogenesis and Bone Regeneration Through Macrophage M1 Polarisation

open access: yesCell Proliferation, EarlyView.
During the early stage of bone defect healing, lactate accumulates and contributes to increasing NOD1 expression by stabilising HIF1α that in turn triggers a calcium influx, which ultimately polarises macrophages towards the M1 phenotype and accelerates vascularisation of endothelial cells.
Lulu Liu   +10 more
wiley   +1 more source

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