Results 51 to 60 of about 23,382 (287)

Development and Implementation of a Geriatric Oncology Interdisciplinary Case–Based Educational Intervention for Cancer Care Providers

JCO Global Oncology
PURPOSETo develop and implement a continuing professional development (CPD) activity focused on geriatric assessment (GA) in oncology for oncologists and geriatricians.
Haydee C. Verduzco-Aguirre, Carolina Gomez-Moreno, Ana P. Navarrete-Reyes, Gretell Henriquez-Santos, Javier Monroy Chargoy, Abigail Mateos-Soria, Juan José Sánchez-Hernández, Alicia Castelo-Loureiro, Liz Hamui-Sutton, Melchor Sánchez-Mendiola, Enrique Soto-Perez-de-Celis   +10 more
doaj   +1 more source

The need for an aging and cancer curriculum for hematology/oncology trainees

, 2010
There has long been recognition for the need of education and training in aging and cancer. As the proportion of older individuals in the United States increases, with 20% being over 65 by 2030, it will become increasingly important for hematology ...
Arti Hurria, Harvey Cohen, Pearl Seo, Heflin, Mitchell, Cohen, Harvey, Seo, Pearl, Rao, Arati, Arati Rao, Hurria, Arti, Mitchell Heflin, Arash Naeim, Naeim, Arash   +11 more
core   +1 more source

The Evolution of Geriatric Oncology and Geriatric Assessment over the Past Decade

, 2022
Cancer is predominantly a disease of aging, and older adults represent the majority of cancer diagnoses and deaths. Older adults with cancer differ significantly from younger patients, leading to important distinctions in cancer treatment planning and ...
Abdallah, Maya, Williams, Grant R., Giri, Smith, Subbiah, Ishwaria M., Marinho, Joana, Hsu, Tina, Tuch, Gina, Outlaw, Darryl, Madureira, Tânia, Liposits, Gabor, Krok-Schoen, Jessica L., Gil-Jr, Luiz A.   +11 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Differences in the symptom experience of older versus younger oncology outpatients: a cross-sectional study

BMC Cancer, 2013
Background Mortality rates for cancer are decreasing in patients under 60 and increasing in those over 60 years of age. The reasons for these differences in mortality rates remain poorly understood.
Cataldo Janine K, Paul Steven, Cooper Bruce, Skerman Helen, Alexander Kimberly, Aouizerat Bradley, Blackman Virginia, Merriman John, Dunn Laura, Ritchie Christine, Yates Patsy, Miaskowski Christine   +11 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

The oncogeriatric transition in Morocco: health-system challenges and strategic priorities in an aging society

Frontiers in Public Health
BackgroundMorocco is experiencing rapid demographic aging alongside a rising cancer burden, creating structural challenges for the care of older adults with cancer.
Oussama Sabri, Oussama Sabri, Halima Abahssain, Halima Abahssain, Wydad Nadir, Sihame Lkhoyaali, Sihame Lkhoyaali, Saber Boutayeb, Saber Boutayeb, Hind Mrabti, Hind Mrabti, Hassan Errihani, Hassan Errihani   +12 more
doaj   +1 more source

Palliative care needs: Symptom reporting during geriatric oncology evaluation.

, 2014
184 Background: Although extensive descriptive work has been conducted on the symptom experience in cancer, relatively little is known about the specific palliative care needs for geriatric oncology populations.
Charles Stewart Kamen, William Dale, Allison Magnuson, Gary R. Morrow, Mohamedtaki Abdulaziz Tejani, Chintan Pandya, Supriya Gupta Mohile, Marie Anne Flannery   +7 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source