Results 131 to 140 of about 64,368 (261)

Alzheimer's Biomarkers and Visuospatial Cognition in Parkinson's Disease: Modification by α‐Synuclein and Mediation of Age Effects

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Visuospatial deficits in Parkinson's disease (PD) often precede dementia and complicate daily functioning. Alzheimer's disease (AD) pathology and α‐synuclein aggregation frequently co‐occur in PD, but their combined impact on cognition is unclear.
David Ledingham   +8 more
wiley   +1 more source

The Impact of Participation in the Parkinson's Pals Program on Psychosocial Symptoms in Parkinson's Disease: An Unblinded Feasibility Study

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Persons with Parkinson's disease (pwPD) frequently experience psychosocial symptoms that are inadequately addressed by traditional clinical approaches. Objectives To evaluate the impact of Parkinson's Pals, a student‐led virtual, intergenerational program, on psychosocial symptoms in pwPD and student knowledge.
Jaskeerat Gujral   +4 more
wiley   +1 more source

Atrial Fibrillation as a Geriatric Syndrome: Why Are Frailty and Disability Often Confused? A Geriatric Perspective from the New Guidelines. [PDF]

open access: yesInt J Environ Res Public Health
Testa C   +8 more
europepmc   +1 more source

Socioeconomic inequalities associated with Geriatric syndrome in Thailand: The results of Fifth National Health Examination Survey. [PDF]

open access: yesPLoS One
Sripaew S   +7 more
europepmc   +1 more source

Clinical and Imaging Characteristics of Parkinson's Disease with Negative Alpha‐Synuclein Seed Amplification Assay

open access: yesMovement Disorders, EarlyView.
Abstract Background The cerebrospinal fluid alpha‐synuclein seed amplification assay (CSFasynSAA) detects alpha‐synuclein aggregation in over 90% of individuals with sporadic PD (sPD). However, the clinical characteristics of sPD with negative CSFasynSAA remain undefined.
Sarah M. Brooker   +30 more
wiley   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur   +6 more
wiley   +1 more source

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