Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi +13 more
wiley +1 more source
Nurse-led geriatric syndrome screening and intervention program for frail older inpatients in Singapore: a study protocol on implementation research and program evaluation. [PDF]
Lim C +12 more
europepmc +1 more source
Estimated impact of model‐guided venous thromboembolism prophylaxis versus real‐world practice
Abstract Background The American Society of Hematology (ASH) recommends assessing venous thromboembolism (VTE) and major bleeding risk to optimize pharmacological VTE prophylaxis for medical inpatients. However, the clinical utility of model‐guided approaches remains unknown.
Benjamin G Mittman, Michael B. Rothberg
wiley +1 more source
Oropharyngeal dysphagia as a geriatric syndrome
Oropharyngeal dysphagia fulfils all the criteria proposed for geriatric syndromes: high prevalence in older persons at different settings, combination of various symptoms, interaction and common risk factors with other geriatric syndromes such as older ...
Mateos-Nozal J., Martos J., Masiero S.
core +1 more source
Upper gastrointestinal bleeding differences between older and younger adults: should bleeding in non-cirrhotic patients be considered a geriatric syndrome? [PDF]
Vara-Luiz F +16 more
europepmc +1 more source
Chronic multisite pain: evaluation of a new geriatric syndrome. [PDF]
Thapa S +4 more
europepmc +1 more source
Bartter's syndrome in a geriatric patient
Kumar, A. C. V. +5 more
openaire +2 more sources
Prevalence and costs of US pediatric hospitalizations, 2022
Abstract Background Pediatric hospitalizations represent an evolving component of US healthcare utilization. The coronavirus disease 2019 (COVID‐19) pandemic hastened rising mental health visits and shrinking rural hospital capacity. Understanding contemporary patterns in pediatric hospitalizations is critical to inform health system planning and ...
Anna J. Lytchakov +5 more
wiley +1 more source
Geriatric syndrome awareness and its determinants in China: a cross-sectional study. [PDF]
Wu D, Yu X, Li F, Qiao W, Chen X.
europepmc +1 more source
Streamlining antibiotic use in community acquired pneumonia: A quality improvement initiative
Abstract Background Evidence suggests a 3‐day total duration and early transition to oral therapy is safe in hospitalized patients with community acquired pneumonia (CAP)—though such care is not standard in the United States. To implement these evidence‐based practices, a multidisciplinary group led by a hospitalist and antimicrobial stewardship ...
Claire E. Ciarkowski +6 more
wiley +1 more source

