Results 31 to 40 of about 64,368 (261)

The relationship between cognitive impairment and the manifestations of geriatric syndrome in elderly and senile individuals living in Arkhangelsk

Российский журнал гериатрической медицины
The aging of the population is an inevitable but predictable process in modern society, both in the Russian Federation and worldwide. With increasing life expectancy, there is a significant increase in conditions and diseases related to frailty and aging.
A. N. Galushin, I. A. Novikova, V. V. Popov   +2 more
doaj   +1 more source

COMPREHENSIVE GERIATRIC ASSESSMENT IN PRACTICE: WHAT DO PATIENTS SAY?

İstanbul Tıp Fakültesi Dergisi, 2022
Objective: Comprehensive Geriatric Assessment (CGA) is one of the cornerstones of geriatric medicine. In this study, we aimed to find out how satisfied patients aged 60 and over with the application of CGA and whether they would express these complaints ...
Tuğba Erdoğan, Birkan İlhan, Aslı Tufan Çinçin, Gülistan Bahat Öztürk, Mehmet Akif Karan   +4 more
doaj   +1 more source

Association of sarcopenia with geriatric syndromes and neutrophil / lymphocyte ratio

Medicine Science, 2022
We aimed to search the relationship of sarcopenia with chronic diseases, geriatric syndromes and neutrophil/lymphocyte ratio (NLR). Our study included 258 patients who were admitted to Cerrahpaşa Medical Faculty geriatrics outpatient clinic for the first
Veysel Suzan, Bahar Bektan Kanat, Hakan Yavuzer   +2 more
doaj   +1 more source

The Oral Anticoagulants Administration in Elderly Patients with Geriatric Syndromes: What's New?

Рациональная фармакотерапия в кардиологии, 2020
The administration of oral anticoagulants in elderly patients with geriatric syndromes such as senile asthenia syndrome, falls and high risk of falls, dementia, polymorbidity, polypharmacy are discussed in the article.
N. M. Vorobyeva, O. N. Tkacheva
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Rapid Geriatric Assessment Using Mobile App in Primary Care: Prevalence of Geriatric Syndromes and Review of Its Feasibility

Frontiers in Medicine, 2020
With the aging population and consequent increase in associated prevalence of frailty, dementia, and multimorbidity, primary care physicians will be overwhelmed with the complexity of the psychosocial and clinical presentation.
Reshma Aziz Merchant, Reshma Aziz Merchant, Richard Jor Yeong Hui, Sing Cheer Kwek, Meena Sundram, Arthur Tay, Jerome Jayasundram, Matthew Zhixuan Chen, Shu Ee Ng, Li Feng Tan, John E. Morley   +10 more
doaj   +1 more source

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

Geriatric Syndromes in Older Adults Hospitalized with COVID-19 in Montreal, Canada

Canadian Geriatrics Journal, 2022
Background Older adults are more vulnerable to severe infection and mortality due to COVID-19. They have atypical presentations of the disease without respiratory symptoms, making early diagnosis clinically challenging.
Sandrine Couture, Marc-Antoine Lepage, Claire Godard-Sebillotte, Nadia Sourial, Catherine Talbot-Hamon, Richard Kremer, Amichai Grunbaum   +6 more
doaj   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

A patient with chronic pain syndrome

Российский журнал гериатрической медицины, 2021
This article describes a clinical case of a patient with chronic pain syndrome on the background of osteoarthritis, with a history of joint replacement.
V. I. Moroz, M.. B. Balaeva, A. V Naumov, N. O. Khovasova   +3 more
doaj   +1 more source