Results 51 to 60 of about 283,457 (303)

Meeting Aging-Related Needs in 2016 [PDF]

, 2017
Our Virginia Center on Aging has four program focuses. These programs are: dementia, elder abuse and domestic violence in later life, geriatrics education, and lifelong learning.
Ansello, Edward F.
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Characteristics of outdoor falls among older people: A qualitative study [PDF]

, 2013
Background Falls are a major threat to older people’s health and wellbeing. Approximately half of falls occur in outdoor environments but little is known about the circumstances in which they occur.
A Bergland, A Nathan, A Shumway-Cook, A Shumway-Cook, A Ståhl, AC King, AH Ranhoff, AL Rosso, AR Eisenstein, AR Levy, C Beynon, C Robson, C Willig, CJ Cherpitel, Claire Ballinger, DC Landy, DE Rosenberg, DL Morgan, E Stack, F Bunn, GJ Wijlhuizen, GJ Wijlhuizen, H-W Wahl, HM Hanson, J Fleming, J Kerr, J Phillips, J Ritchie, J Ritchie, JL Kelsey, JL Kelsey, JL Kelsey, Judith E Phillips, K Horton, K Sjogren, KR Fox, L Asher, L Clemson, L Clemson, L Gauvin, L Salonen, L Yardley, L Yardley, LA Talbot, LD Gillespie, M Annear, M Rantakokko, M Rantakokko, M Rantakokko, M Rantakokko, MC Nevitt, MG Davis, MHC Bleijlevens, MRU Meyer, N Owen, NM Peel, O Beauchet, P Morency, PA Bath, Panel on Prevention of Falls in Older Persons, American Geriatrics Society, British Geriatrics Society, PC Lai, PC Lai, R Newton, Rita Newton, S Turner, S Wilkinson, Samuel R Nyman, SC Webber, SE Lamb, SR Cummings, SR Lord, SR Lord, TE Finnes, W Li, World Health Organization, Y Rydin, YH Chu, YL Michael   +77 more
core   +2 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Integrating Geriatrics in Primary Care: Progress and Prospects [PDF]

, 2017
Educational Objectives 1. Demonstrate the need for primary care redesign to better meet the needs of older patients. 2. Identify prospective redesign solutions. 3.
Bluestein, Daniel A., Diduk-Smith, Ryan M.   +1 more
core   +1 more source

The role of concern about falling on stepping performance during complex activities [PDF]

, 2019
Background There is limited understanding of the underlying mechanisms explaining the role of concern about falling on fall risk in older people. Anxiety is known to interact with cognitive resources and, as people get older, they require more cognitive ...
Brodaty, Henry, Close, Jacqueline C. T., Crombez, Geert, Delbaere, Kim, Lord, Stephen R., Sachdev, Perminder, Viaje, Shaira   +6 more
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Preparing Family Caregivers to Recognize Delirium Symptoms in Older Adults After Elective Hip or Knee Arthroplasty [PDF]

, 2017
Objectives To test the feasibility of a telephone-based intervention that prepares family caregivers to recognize delirium symptoms and how to communicate their observations to healthcare providers.
Boaz, Lesley, Bull, Margaret J., Gettrust, Lynn, Greene, Maureen T., Hagle, Mary E., Holmes, Sue Baird, Maadooliat, Mehdi, Saczynski, Jane S.   +7 more
core   +1 more source

The choice of self-rated health measures matter when predicting mortality: evidence from 10 years follow-up of the Australian longitudinal study of ageing [PDF]

, 2016
BACKGROUND Self-rated health (SRH) measures with different wording and reference points are often used as equivalent health indicators in public health surveys estimating health outcomes such as healthy life expectancies and mortality for older adults ...
Anstey, Kaarin, Luszcz, Mary A, Sargent-Cox, Kerry A   +2 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source