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Surgical Clinics of North America, 2006
The category of germ cell tumors includes a broad array of histologic subtypes ranging from the benign, mature teratoma to the primitive, aggressive embryonal carcinoma (Box 1). These tumors share their origin in a primordial germ cell with multipotent capacity for differentiation along a variety of pathways.
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The category of germ cell tumors includes a broad array of histologic subtypes ranging from the benign, mature teratoma to the primitive, aggressive embryonal carcinoma (Box 1). These tumors share their origin in a primordial germ cell with multipotent capacity for differentiation along a variety of pathways.
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Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms.
Science, 1990D. Malkin +9 more
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Human Genetics, 1998
Mosaicism in germ cells has been recognized, over the past few years, as an important and relatively frequent mechanism at the origin of genetic disorders. There are two possibilities for the existence of such a mosaicism: one is that the mutation occurs in a germ cell that continues to divide.
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Mosaicism in germ cells has been recognized, over the past few years, as an important and relatively frequent mechanism at the origin of genetic disorders. There are two possibilities for the existence of such a mosaicism: one is that the mutation occurs in a germ cell that continues to divide.
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2006
Primordial germ cells, which carry the responsibility for perpetuation of the species, are set aside from their somatic neighbors very early in mammalian embryonic development. The founder population of germ cells is rare and difficult to identify and isolate in quantities suitable for molecular and biochemical analysis, thereby highlighting the ...
Niels, Geijsen, George Q, Daley
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Primordial germ cells, which carry the responsibility for perpetuation of the species, are set aside from their somatic neighbors very early in mammalian embryonic development. The founder population of germ cells is rare and difficult to identify and isolate in quantities suitable for molecular and biochemical analysis, thereby highlighting the ...
Niels, Geijsen, George Q, Daley
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Hematology/Oncology Clinics of North America, 1992
The development of modern surgical staging and effective chemotherapy regimens has markedly improved outcome of treatment of ovarian germ cell tumors. Almost all patients with completely resected tumors will survive their disease. Those with tumors other than dysgerminoma should all receive adjuvant chemotherapy. Patients with stage IA dysgerminoma can
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The development of modern surgical staging and effective chemotherapy regimens has markedly improved outcome of treatment of ovarian germ cell tumors. Almost all patients with completely resected tumors will survive their disease. Those with tumors other than dysgerminoma should all receive adjuvant chemotherapy. Patients with stage IA dysgerminoma can
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THE EFFECTS OF SURGICAL EXPOSURES OF DENTAL PULPS IN GERM-FREE AND CONVENTIONAL LABORATORY RATS.
Oral surgery, oral medicine, and oral pathology, 1965S. Kakehashi, H. Stanley, R. Fitzgerald
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Bax-Deficient Mice with Lymphoid Hyperplasia and Male Germ Cell Death
Science, 1995C. Knudson +4 more
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