Results 41 to 50 of about 294,684 (293)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Poner el cuidado y el afecto en el centro de la pedagogía

open access: yesVoces de la educación, 2021
El presente trabajo intenta reflexionar sobre la importancia pedagógica del afecto y del cuidado, no sólo en tiempos de pandemia, sino como elemento clave, aunque olvidado, del proceso educativo. Para ello, se expondrán las consecuencias de la pandemia y
José Félix Angulo Rasco
doaj  

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Simbolika orla in sonca v emblemih Spominske knjige ljubljanske plemiške družbe sv. Dizma

open access: yesArs & Humanitas, 2020
Avtor v svoji študiji analizira ročno slikane embleme z motivom orla in sonca v Spominski knjigi ljubljanske plemiške družbe sv. Dizma (skrajšano: Dizmova kronika), hranjene v Arhivu Republike Slovenije (ref. AS 1073, I/1), ki so z ikonografskega vidika
Tine Germ
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Improving Fermentation Rate during Use of Corn Grits in Beverage Alcohol Production

open access: yesBeverages, 2019
Corn grits are commonly used adjuncts in the brewing industry in the United States, especially for lager beers. The major challenge of using a high amount of adjuncts in the brewing process is reduced levels of nutrients available to yeast during ...
Deepak Kumar   +5 more
doaj   +1 more source

The selfish germ

open access: yesPLOS Biology, 2017
Curiosity about the sex life of a wasp led to a new way of thinking and a powerful demonstration that evolutionary science could be predictive. That same approach could help find ways to slow or prevent treatment failures in cancer and infectious diseases.
openaire   +5 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Teratoma adultum in a bitch: a case report

open access: yesVeterinární Medicína, 2009
This case report concerns a two year old female mongrel weighing about 25 kg which was admitted to an animal shelter. A grapefruit-sized mass was found in the animal's left ovary during a routinely performed ovariohysterectomy.
B. Blaszak   +3 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

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