Results 41 to 50 of about 11,144,846 (357)
Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice
Cell Death and Disease, 2015 Primary ovarian insufficiency (POI) is a common cause of infertility in around 1–2% of women aged
Zhi-Hui Song +11 more
semanticscholar +1 more source
Postnatal germ cell development in cryptorchid boys
Asian Journal of Andrology, 2020 Cryptorchidism is associated with infertility in adulthood. Early orchiopexy is suggested to reduce the risk. Information is lacking on the potential link between infant germ cell maturation and the risk of future infertility.
Li-Hua Dong +6 more
doaj +1 more source
Frequent PD-L1 expression in testicular germ cell tumors
British Journal of Cancer, 2015 Background:Many testicular germ cell cancers are curable despite metastatic disease, but about 10–15% of patients fail cisplatin-based first-line treatment. Immunotherapy is considered as additional treatment approach for these patients.
C. Fankhauser +7 more
semanticscholar +1 more source
Cooperative cell–cell actin network remodeling to perform Gap junction endocytosis
Basic and Clinical Andrology, 2023 Background The endocytosis of Gap junction plaques (GJP) requires cytoskeletal forces to internalize such large membranous structures. Actin, which partners the connexin proteins constituting Gap junctions and is located close to Annular Gap Junctions ...
Dominique Segretain +5 more
doaj +1 more source
Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile
EMBO Journal, 2015 Primordial germ cells (PGCs) develop only into sperm and oocytes in vivo. The molecular mechanisms underlying human PGC specification are poorly understood due to inaccessibility of cell materials and lack of in vitro models for tracking the earliest ...
Fumihiro Sugawa +9 more
semanticscholar +1 more source
Primary Germ Cell Tumors of the Mediastinum: 10 Years of Experience in a Tertiary Teaching Hospital
Kaohsiung Journal of Medical Sciences, 2005 Germ cell tumors occur mostly in the gonad. Extragonadal germ cell tumors are rare, and most occur in the retroperitoneum and mediastinum. Primary mediastinal germ cell tumors are often found in the anterior portion of the mediastinum and include ...
Chih-Jen Yang +2 more
doaj +1 more source
Identification of a putative germ plasm in the amphipod Parhyale hawaiensis [PDF]
, 2014 Background: Specification of the germ line is an essential event during the embryonic development of sexually reproducing animals, as germ line cells are uniquely capable of giving rise to the next generation.
Extavour, Cassandra G, Gupta, Tripti
core +1 more source
Czech Journal of Animal Science, 2017 Pikeperch Sander lucioperca is a valuable fish in Europe, and basic information about its embryonic development, especially primordial germ cell (PGC) migration, is important for use in biotechnology.
Hilal Güralp +5 more
doaj +1 more source
Doxorubicin Affects Testicular Lipids with Long-Chain (C18-C22) and Very Long-Chain (C24-C32) Polyunsaturated Fatty Acids [PDF]
, 2007 Doxorubicin disrupts spermatogenesis by causing apoptosis of spermatogonia and primary spermatocytes. The aim of this study was to examine the effect of this agent on adult rat testicular lipids and their fatty acids.
Aveldaño, Marta Isabel +2 more
core +1 more source
PLoS Genetics, 2015 piRNAs are critical for transposable element (TE) repression and germ cell survival during the early phases of spermatogenesis, however, their role in adult germ cells and the relative importance of piRNA methylation is poorly defined in mammals. Using a
S. Lim +14 more
semanticscholar +1 more source