Germ cell markers in fishes - A review
Identification of germ cell markers in fishes is crucial to track the germ cell differentiation and migration for manipulation of the cells to study sexual differentiation as well as to carry out transgenic transplantation techniques.
Sultana Begum+3 more
doaj
Transcription factor TFAP2C regulates major programs required for murine fetal germ cell maintenance and haploinsufficiency predisposes to teratomas in male mice. [PDF]
Maintenance and maturation of primordial germ cells is controlled by complex genetic and epigenetic cascades, and disturbances in this network lead to either infertility or malignant aberration.
Jana Schemmer+9 more
doaj +1 more source
Spermatogenesis and sertoli cell activity in mice lacking Sertoli cell receptors for follicle stimulating hormone and androgen [PDF]
Spermatogenesis in the adult male depends on the action of FSH and androgen. Ablation of either hormone has deleterious effects on Sertoli cell function and the progression of germ cells through spermatogenesis.
A. Monteiro+63 more
core +2 more sources
Phase transitioned nuclear Oskar promotes cell division of Drosophila primordial germ cells
Germ granules are non-membranous ribonucleoprotein granules deemed the hubs for post-transcriptional gene regulation and functionally linked to germ cell fate across species.
Kathryn E Kistler+7 more
doaj +1 more source
Postnatal germ cell development in cryptorchid boys
Cryptorchidism is associated with infertility in adulthood. Early orchiopexy is suggested to reduce the risk. Information is lacking on the potential link between infant germ cell maturation and the risk of future infertility.
Li-Hua Dong+6 more
doaj +1 more source
Meiotic wave adds extra asymmetry to the development of female chicken gonads [PDF]
Development of female gonads in the chicken is asymmetric. This asymmetry affects gene expression, morphology, and germ cell development; consequently only the left ovary develops into a functional organ, whereas the right ovary remains vestigial.
Anjie, Stafford+8 more
core +2 more sources
Expression of Axolotl DAZL RNA, a Marker of Germ Plasm: Widespread Maternal RNA and Onset of Expression in Germ Cells Approaching the Gonad [PDF]
How germ cell specification occurs remains a fundamental question in embryogenesis. The embryos of several model organisms contain germ cell determinants (germ plasm) that segregate to germ cell precursors.
Bachvarova, Rosemary F.+3 more
core +1 more source
Pikeperch Sander lucioperca is a valuable fish in Europe, and basic information about its embryonic development, especially primordial germ cell (PGC) migration, is important for use in biotechnology.
Hilal Güralp+5 more
doaj +1 more source
The germ cell-less gene belongs to the BTB/POZ protein-family, whose structural domain plays an important role in the occurrence of mammalian gonads as it specifically combines with other DNA proteins. In this study, a unigene annotated as germ cell-less
Xiaoxiao HUANG+5 more
doaj +1 more source
LIN28 is selectively expressed by primordial and pre-meiotic germ cells in the human fetal ovary [PDF]
Germ cell development requires timely transition from primordial germ cell (PGC) self-renewal to meiotic differentiation. This is associated with widespread changes in gene expression, including downregulation of stem cell–associated genes, such as OCT4 ...
Anderson, Richard A+3 more
core +1 more source