Results 41 to 50 of about 238,883 (265)

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Label-free metabolic fingerprinting of motile mammalian spermatozoa with subcellular resolution

BMC Biology
Background Sperm metabolic pathways that generate energy for motility are compartmentalized within the flagellum. Dysfunctions in metabolic compartments, namely mitochondrial respiration and glycolysis, can compromise motility and male fertility ...
Fitore Kusari, Lenka Backova, Dalibor Panek, Ales Benda, Zdenek Trachtulec   +4 more
doaj   +1 more source

In vitro germ cell differentiation from cynomolgus monkey embryonic stem cells. [PDF]

PLoS ONE, 2009
BACKGROUND: Mouse embryonic stem (ES) cells can differentiate into female and male germ cells in vitro. Primate ES cells can also differentiate into immature germ cells in vitro.
Kaori Yamauchi, Kouichi Hasegawa, Shinichiro Chuma, Norio Nakatsuji, Hirofumi Suemori   +4 more
doaj   +1 more source

Prolonged fasting induces significant germ cell loss in chickens after hatching

Poultry Science, 2023
: Germ cell loss is a crucial biological event during germ cell development. The number of female germ cells determines the reproductive performance and egg production of hens.
Jiawen Chen, Liping Pu, Yajing Niu, Kui Tian, Xiaoxuan Jia, Lang Zhang, Yangqing Lu   +6 more
doaj   +1 more source

Phase Angle as an Early Functional Biomarker of Cancer‐Related Fatigue in Pediatric Oncology: A Prospective Longitudinal Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric cancer remains a leading cause of morbidity and mortality worldwide, particularly in low‐and middle‐income countries. Cancer treatment may impair nutritional status, alter body composition, and exacerbate cancer‐related fatigue (CRF).
Luís Carlos Lopes‐Junior, Luiz Claudio Barreto Silva Neto, Fabiano Kenji Haraguchi, Letícia Batista de Azevedo, Marcelo Brenner Nascimento Carlini, Raphael Manhães Pessanha, Mariana Rabello Laignier, Wesley Rocha Grippa, Tania Mara Lopes Bitti Bortolini, Gláucia Zouain‐Figueiredo, Regina Aparecida Garcia de Lima, Liliana Vasquez   +11 more
wiley   +1 more source

Seasonal composition of immature germ cells in the Yesso scallop identified by vasa-like gene (my-vlg) and protein expression, with evidence of irregular germ cell differentiation accompanied with a high mortality event

Aquaculture Reports, 2021
The objective of this study was to understand germ cell renewal and differentiation in the Yesso scallop Mizuhopecten yessoensis throughout its reproductive cycle.
Mariia Mokrina, Kazue Nagasawa, Makoto Kanamori, Masafumi Natsuike, Makoto Osada   +4 more
doaj   +1 more source

A role for Lin28 in primordial germ-cell development and germ-cell malignancy [PDF]

Nature, 2009
The rarity and inaccessibility of the earliest primordial germ cells (PGCs) in the mouse embryo thwart efforts to investigate molecular mechanisms of germ-cell specification. stella (also called Dppa3) marks the rare founder population of the germ lineage.
West, Jason A., Viswanathan, Srinivas R., Yabuuchi, Akiko, Cunniff, Kerianne, Takeuchi, Ayumu, Park, In-Hyun, Sero, Julia E., Zhu, Hao, Perez-Atayde, Antonio, Frazier, A. Lindsay, Surani, M. Azim, Daley, George Q.   +11 more
openaire   +2 more sources

Time to Diagnosis Among Children and Adolescents With Cancer in Québec, Canada: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen, Ronald D. Barr, Erin Strumpf, Mariam El‐Zein, Eduardo L. Franco, Talía Malagón   +5 more
wiley   +1 more source

The fate of germ cells in cryptorchid testis

Frontiers in Endocrinology
Cryptorchidism in males constitutes a notable risk factor for both infertility and testicular cancer. Infertility in adulthood is closely linked to the germ cell status in childhood.
Jorgen Thorup, Jorgen Thorup, Simone Hildorf, Andrea E. Hildorf, Jonas M. Baastrup, Linn Salto Mamsen, Claus Yding Andersen, Tina E. Olsen, Dina Cortes, Dina Cortes   +9 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source