a report from the Children's Oncology Group and the Utah Population Database [PDF]
Relatively little is known about the epidemiology and factors underlying susceptibility to childhood rhabdomyosarcoma (RMS). To better characterize genetic susceptibility to childhood RMS, we evaluated the role of family history of cancer using data from
Curtin, Karen +13 more
core +1 more source
Gastric teratoma in a 6-month-old boy
Gastric teratomas are very rare embryonal neoplasms, accounting for 2.6% of all perinatal diagnosed germ cell tumours. About 85% are well-differentiated mature lesions and about 15% are immature tumours with the potential of malignant transformation. The
Peer Wildbrett +4 more
doaj +1 more source
Testicular germ-cell tumours and penile squamous cell carcinoma: Appropriate management makes the difference [PDF]
Germ-cell tumours (GCT) of the testis and penile squamous cell carcinoma (PeSCC) are a rare and a very rare uro-genital cancers, respectively. Both tumours are well defined entities in terms of management, where specific recommendations - in the form of ...
Almar E. +121 more
core +1 more source
Perspectives on testicular sex cord-stromal tumors and those composed of both germ cells and sex cord-stromal derivatives with a comparison to corresponding ovarian neoplasms [PDF]
Sex cord-stromal tumors (SCSTs) are the second most frequent category of testicular neoplasms, accounting for approximately 2–5% of cases. Both genetic and epigenetic factors account for the differences in frequency and histologic composition between ...
Cheng, Liang +2 more
core +1 more source
ATRT-15. Primordial germ cells identified as one potential cell of origin of MYC rhabdoid tumors
Rhabdoid tumors (RT) are embryonal neoplasms occurring most frequently in the central nervous system where they are termed atypical teratoid rhabdoid tumor (ATRT). A common hallmark of RT is homozygous loss of the BAF complex subunit SMARCB1.
M. Graf +24 more
semanticscholar +1 more source
Pluripotent human stem cells: Standing on the shoulders of giants [PDF]
The advent of human pluripotent stem cells, with the first derivation of human embryonic stem cells in 1998, and of human induced pluripotent stem cells in 2007, has ushered in an era of considerable excitement about the prospects of using these cells to
Andrews, P.W., Damjanov, I.
core +1 more source
Malignant mixed ovarian germ cell tumours, typically present in the teenage years, are a rare group of rapidly growing and highly aggressive neoplasms that are derived from the primitive germ cells of the embryonal gonad representing 5% of all malignant ...
Emilio M. Treviño-Salinas +6 more
semanticscholar +1 more source
A prospective study on contrast-enhanced magnetic resonance imaging of testicular lesions: distinctive features of Leydig cell tumours [PDF]
OBJECTIVES: Up to 20 % of incidentally found testicular lesions are benign Leydig cell tumours (LCTs). This study evaluates the role of contrast-enhanced magnetic resonance imaging (MRI) in the identification of LCTs in a large prospective cohort study.
BERNARDO, SILVIA +11 more
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GnRH-independent precocious puberty (GIPP) can be the presenting clinical picture experienced by patients with secreting germ cell tumor (GCT). Indeed, as luteinizing hormone (LH) and human chorionic gonadotropin (hCG) share identical α-subunits and ...
Alessandro Cattoni +2 more
doaj +1 more source
A multi-disciplinary Delphi method to identify consensus in the management of intracranial germ cell tumours [PDF]
The management of intracranial germ-cell tumours is complex because of varied clinical presentations, tumour sites, treatments and outcomes, and the need for multidisciplinary input.
Bartels, Ute +5 more
core +1 more source

