Results 11 to 20 of about 11,695 (262)

Giant Mediastinal Teratoma in a Child: A Case Report With a Brief Review of the Literature

Clinical Case Reports
Giant mediastinal teratomas in the pediatric population are uncommon entities that may grow insidiously and cause significant compression of intrathoracic structures.
Urías Hernandez Lopez, Pastor Thomas Olivares, Alex Fernández Arrieta, Juan Correa Palacio, Aura Guevara Díaz, Ana Guerra Urquijo   +5 more
doaj   +2 more sources

Targeting Cancer Stem Cells with Differentiation Agents as an Alternative to Genotoxic Chemotherapy for the Treatment of Malignant Testicular Germ Cell Tumors

Cancers, 2021
Simple Summary Testicular germ cell tumors (TGCTs) are the most common solid malignancy in young men. Fortunately, these tumors are highly curable with conventional genotoxic chemotherapy.
A. Loehr, Timothy M. Pierpont, Eric Gelsleichter, A. M. D. Galang, Irma R. Fernandez, Elizabeth S. Moore, M. Guo, Andrew D. Miller, R. Weiss   +8 more
semanticscholar   +1 more source

Malignant mixed germ cell tumours- A rare case report with unusual presentation in a 05 years old female child

Indian Journal of Pathology and Oncology, 2021
Mixed germ cell tumours (MGCT) of the ovary are malignant neoplasms of the ovary comprising of two or more types of germ cell components. Most of the malignant MGCT consists of dysgerminoma accompanied by endodermal sinus tumours, immature teratoma or ...
Ritu Sonkar, Harendra Kumar, Pooja Nagayach, P. Srivastava   +3 more
semanticscholar   +1 more source

Extragonadal germ-cell tumors – a review of the pathogenesis, histopathological findings, diagnosis and treatment [PDF]

Archives of the Balkan Medical Union, 2019
Primary extragonadal germ-cell tumors (EGCTs) are a rare group of neoplasms, that can exist anywere along the midline of the body, without the evidence of a primary gonadal tumor.
Lucian IORGA, Dragos MARCU, Ovidiu BRATU, Bogdan SOCEA, Tiberiu P. NEAGU, Simona BUNGAU, Ana Maria A. STANESCU, Camelia C. DIACONU, Dan MISCHIANU   +8 more
doaj   +1 more source

Prognostic factors in children with extracranial germ cell tumors treated with cisplatin-based chemotherapy [PDF]

Korean Journal of Pediatrics, 2015
PurposeTo evaluate the outcomes and prognostic factors in children with extracranial germ cell tumors (GCTs) treated at a single institution.MethodsSixty-six children diagnosed with extracranial GCTs between 1996 and 2012 were included in the study ...
Jinsup Kim, Na Hee Lee, Soo Hyun Lee, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo, Jeong-Meen Seo, Suk-Koo Lee   +7 more
doaj   +1 more source

Exploring the interdependencies of research funders in the UK [PDF]

, 2014
Investment in medical research is vital to the continuing improvement of the UK's health and wealth. It is through research that we expand our understanding of disease and develop new treatments for patients.
Crane, P, Farrell, C, Garau, M, Grassano, N, Hernandez-Villafuerte, K, Hopkins, M M, Hutton, J, Lang, F, Mawer, A, Pateman, C, Rotolo, D, Shah, K, Sharp, T, Sussex, J   +13 more
core   +1 more source

PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation. [PDF]

, 2018
Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate.
Chen, Di, Clark, Amander T, Gell, Joanna J, Hunt, Timothy J, Zhao, Jasmine   +4 more
core   +2 more sources

Identification of ERβ1 and ERβ2 in human seminoma, in embryonal carcinoma and in their adjacent intratubular germ cell neoplasia

Reproductive Biology and Endocrinology, 2009
Background Estrogens exert a role on germ cell physiology of normal human testis through the mediation of the estrogen receptor (ER) beta subtypes. Epidemiological studies evidenced an increased incidence of testicular germ cell cancer after elevated pre-
Rago Vittoria, Romeo Francesco, Giordano Francesca, Ferraro Aurora, Andò Sebastiano, Carpino Amalia   +5 more
doaj   +1 more source

A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report

Journal of Cardiothoracic Surgery, 2023
Background Teratoma is a type of germ cell tumor consisting of one or multiple tissues derived from germinal layers. The location and size of the tumor can cause various presentations.
Parviz Mardani, Hooman Kamran, Rezvan Ghaderpanah, Bita Geramizadeh, Damoun Fouladi, Reza Shahriarirad, Armin Amirian   +6 more
doaj   +1 more source

Neonates with cancer and causes of death; lessons from 615 cases in the SEER databases [PDF]

, 2017
Neonatal tumors are rare with no standard treatment approaches to these diseases, and the patients experience poor outcomes. Our aim was to determine the distribution of cancers affecting neonates and compare survival between these cancers and older ...
Askin, Bresters, Buck, Drazen, Ferrari, Gigliotti, Isaacs, Isaacs, Isaacs, Isaacs, Johnson, Linden, Longo, Louis, Mili, Moore, Moore, Oi, Orbach, Parkes, Rankin, Roosen, Sande, Steliarova-Foucher, Thompson, Vormoor, Yu   +26 more
core   +1 more source