Results 11 to 20 of about 8,962 (171)

Higher LSD1 in Non-Seminomatous Germ Cell Tumors and LSD1 Inhibition by NCL1 Suppresses Embryonal Carcinoma Growth. [PDF]

Cancer Sci
LSD1 expression was higher in non‐seminomatous than in seminomatous testicular germ cell tumor components. In embryonal carcinoma models, selective LSD1 inhibition by NCL1 induced epigenetic and apoptotic responses, reduced viability including in cisplatin‐adapted cells, and suppressed early xenograft outgrowth, supporting LSD1 as a potential ...
Shimizu N, Etani T, Naiki T, Naiki-Ito A, Sugiyama Y, Nagai T, Murakami A, Kato H, Morikawa T, Aoki M, Gonda M, Suzuki H, Tsubouchi Y, Ishikawa D, Suzuki T, Takahashi S, Yasui T.   +16 more
europepmc   +2 more sources

Proton beam therapy in paediatric cancer: Anticipating the opening of the Australian Bragg Centre for Proton Therapy and Research

Journal of Medical Imaging and Radiation Oncology, EarlyView., 2023
Summary Proton Beam Therapy (PBT) has the potential to improve paediatric cancer care by reducing radiation exposure and thus long‐term toxicities. Ethical concerns and debates surrounding the treatment, such as eligibility and accessibility, are ongoing in Australia. The Australian Bragg Centre for Proton Therapy and Research (ABCPTR) (named after Sir
Jeremy Khong, Hui Tee, Peter Gorayski, Hien Le, Michael Penniment, Sophie Jessop, Jordan Hansford, Melanie Penfold, Julia Green, Kelly Skelton, Frank Saran   +10 more
wiley   +1 more source

A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report

Journal of Cardiothoracic Surgery, 2023
Background Teratoma is a type of germ cell tumor consisting of one or multiple tissues derived from germinal layers. The location and size of the tumor can cause various presentations.
Parviz Mardani, Hooman Kamran, Rezvan Ghaderpanah, Bita Geramizadeh, Damoun Fouladi, Reza Shahriarirad, Armin Amirian   +6 more
doaj   +1 more source

A case series and literature review on 98 pediatric patients of germ cell tumor developing growing teratoma syndrome

Cancer Medicine, 2023
Introduction Malignant germ cell tumors (MGCTs) can develop either extracranially or intracranially. Growing teratoma syndrome (GTS) may develop in these patients following chemotherapy.
Ming‐Yun Hsieh, Hsin‐Hung Chen, Chih‐Ying Lee, Giun‐Yi Hung, Tsung‐Yen Chang, Shih‐Hsiang Chen, Jin‐Yao Lai, Tang‐Her Jaing, Chao‐Neng Cheng, Jiann‐Shiuh Chen, Hsin‐Lin Tsai, Ting‐Yen Yu, Ming‐Hsin Hou, Cheng‐Yin Ho, Hsiu‐Ju Yen   +14 more
doaj   +1 more source

A Case of Sarcoidosis Disseminated to Skeletal Tissues

International Journal of Medical Students, 2013
Sarcoidosis is a systemic granulomatous disease of unknown etiology that typically affects young adults. Diagnostic criteria for sarcoidosis include involvement of two or more of the following organ systems: 1) pulmonary infiltrates; 2) bilateral hilar ...
Edon Rabinowitz, Chinwe Ogedegbe, Joseph Feldman   +2 more
doaj   +1 more source

Interpretation on embryonal tumors in the 2021 WHO Classification of Tumors of the Central Nervous System (fifth edition)

Chinese Journal of Contemporary Neurology and Neurosurgery, 2021
Embryonal tumors of central nervous system (CNS) are a class of highly heterogeneous brain tumors and the most common malignant brain tumors in children. Researches based on histology and molecular genetics can classify them. This kind of researches only
WANG Yang
doaj   +1 more source

Gastric teratoma in a 6-month-old boy

African Journal of Paediatric Surgery, 2012
Gastric teratomas are very rare embryonal neoplasms, accounting for 2.6% of all perinatal diagnosed germ cell tumours. About 85% are well-differentiated mature lesions and about 15% are immature tumours with the potential of malignant transformation. The
Peer Wildbrett, Hagen Graf Einsiedel, Björn Lange, Holger Lode, Winfried Barthlen   +4 more
doaj   +1 more source

Malignant Ovarian Mixed Germ Cell Tumor: a Rare Case [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2009
Background and Objectives: Mixed germ cell tumors of the ovary, uncommon but aggressive tumors are seen most often in young women or adolescent girls, and are generally curable if found and treated early.
Z. Ebrahimi, Z. Khalaji Nia
doaj  

Low‐grade glial neoplasms of germ cell origin may represent maturation of embryonic‐type neuroectodermal elements

Histopathology
Aims Glial tumours of germ cell origin are relatively rare in men, occurring predominantly after chemotherapy. Many exhibit low‐grade histological features within a spectrum that includes teratomas with mature glial/ganglioglial elements and pure low‐grade tumours with glial/ganglioglial phenotype (LGGT) that ...
João Lobo, Nuno Tiago Tavares, Fernanda Fernandes‐Pontes, Carmen Jerónimo, Rui Henrique, Yiying Yang, Matija Snuderl, Melissa Hruby, Muhammad T Idrees, Thomas M Ulbright, Andres M Acosta   +10 more
openaire   +2 more sources

Erectile Dysfunction in Germ Cell Tumor Survivors

The World Journal of Men's Health, 2021
Purpose: Germ cell tumors (GCTs) are the most common malignant neoplasms in adolescents and young adults, and most patients with these tumors can be completely cured. Therefore, maintaining quality of life (QOL) is important.
Koichi Okada, Kazutoshi Fujita, Shinichiro Fukuhara, Hiroshi Kiuchi, Motohide Uemura, Ryoichi Imamura, Norio Nonomura   +6 more
doaj   +1 more source