PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation [PDF]
Stem Cell Research, 2018 Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate.
Joanna J. Gell +4 more
doaj +4 more sources
Testicular Embryonal Carcinoma With Retroperitoneal Metastasis and Normal AFP and HCG: A Case Report [PDF]
Case Reports in Oncological MedicineTesticular germ cell tumors are common malignant tumors in young men, among which embryonal carcinoma, as an important subtype of non-seminomatous germ cell tumors, is usually accompanied by elevated serum tumor markers.
Panpan Teng, Mingxi Yang, Shang Song
doaj +2 more sources
Epigenetic markers in the embryonal germ cell development and spermatogenesis
Basic and Clinical Andrology, 2023 Résumé La spermatogenèse est le processus de génération de cellules reproductrices mâles à partir de cellules souches spermatogoniales, dans l’épithélium séminifère du testicule.
Amadeusz Odroniec +2 more
doaj +3 more sources
Diagnosis, treatment, and long-term follow-up of a 13-year-old boy with a testicular mixed germ cell tumor (yolk sac tumor and embryonal carcinoma): a case report and literature review [PDF]
Frontiers in PediatricsTesticular germ cell tumors (TGCTs) are rare in children under 15 years of age. We report the first documented case of a mixed yolk sac tumor and embryonal carcinoma in the left testis of a 13-year-old boy in the early stages of puberty (12–14 years ...
Jing Yang +3 more
doaj +2 more sources
Diagnosis and management of a rare bilateral ovarian mixed germ cell tumor: a case report [PDF]
Frontiers in OncologyBackgroundMixed ovarian malignant germ cell tumors (MOGCTs) are rare neoplasms composed of two or more malignant germ cell components, representing less than 1% of all ovarian germ cell tumors.
Xuanling Li +6 more
doaj +2 more sources
A rare case of pure-type embryonal carcinoma in a 75-year-old woman mimicking epithelial ovarian carcinoma [PDF]
Kosin Medical Journal, 2022 Embryonal carcinoma, a very rare ovarian germ cell tumor, involves pure and mixed phenotypes. Pure-type embryonal carcinoma has never been reported in postmenopausal women. The current case was, thus, misdiagnosed as an epithelial ovarian carcinoma based
Hyun Been Jo +7 more
doaj +1 more source
Survival of Testicular Pure Embryonal Carcinoma vs. Mixed Germ Cell Tumor Patients across All Stages
Medicina, 2023 Background and Objectives: The impact of pure histological subtypes in testicular non-seminoma germ cell tumors on survival, specifically regarding pure embryonal carcinoma, is not well established.
Cristina Cano Garcia +19 more
doaj +1 more source
Mixed Germ Cell Tumour in an Infertile Male Having Unilateral Cryptorchidism: A Rare Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2016 Mixed germ cell tumours with multiple components occur more frequently than the pure varieties of germ cell tumours. Embryonal carcinoma and teratoma together form the most common components of the mixed germ cell tumour but the yolk sac tumour is ...
Anand Singla +3 more
doaj +1 more source
Revista do Colégio Brasileiro de Cirurgiões, 2022 Introduction: sacrococcygeal teratoma (TSC) is the most common tumor of the neonatal period. Alphafetoprotein is an important tumor marker and is used in the follow-up period as a marker of malignancy.
VANESSA DO NASCIMENTO SANTOS +2 more
doaj +2 more sources
Germ cells from mouse and human embryonic stem cells [PDF]
Reproduction, 2006 Mammalian gametes are derived from a founder population of primordial germ cells (PGCs) that are determined early in embryogenesis and set aside for unique development. Understanding the mechanisms of PGC determination and differentiation is important for elucidating causes of infertility and how endocrine disrupting chemicals may potentially increase ...
Behrouz, Aflatoonian, Harry, Moore
openaire +2 more sources