Results 1 to 10 of about 13,787 (250)

Survival of Testicular Pure Embryonal Carcinoma vs. Mixed Germ Cell Tumor Patients across All Stages

Medicina, 2023
Background and Objectives: The impact of pure histological subtypes in testicular non-seminoma germ cell tumors on survival, specifically regarding pure embryonal carcinoma, is not well established.
Cristina Cano Garcia, Andrea Panunzio, Stefano Tappero, Mattia Luca Piccinelli, Francesco Barletta, Reha-Baris Incesu, Kyle W. Law, Lukas Scheipner, Zhe Tian, Fred Saad, Shahrokh F. Shariat, Derya Tilki, Alberto Briganti, Ottavio De Cobelli, Carlo Terrone, Alessandro Antonelli, Severine Banek, Luis A. Kluth, Felix K. H. Chun, Pierre I. Karakiewicz   +19 more
doaj   +4 more sources

Molecular and epigenetic pathogenesis of germ cell tumors

Asian Journal of Urology, 2021
The development of germ cell tumors (GCTs) is a unique pathogenesis occurring at an early developmental stage during specification, migration or colonization of primordial germ cells (PGCs) in the genital ridge.
Melanie R. Müller, Margaretha A. Skowron, Peter Albers, Daniel Nettersheim   +3 more
doaj   +2 more sources

PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation [PDF]

Stem Cell Research, 2018
Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate.
Joanna J. Gell, Jasmine Zhao, Di Chen, Timothy J. Hunt, Amander T. Clark   +4 more
doaj   +2 more sources

Identification of ERβ1 and ERβ2 in human seminoma, in embryonal carcinoma and in their adjacent intratubular germ cell neoplasia [PDF]

Reproductive Biology and Endocrinology, 2009
Background Estrogens exert a role on germ cell physiology of normal human testis through the mediation of the estrogen receptor (ER) beta subtypes. Epidemiological studies evidenced an increased incidence of testicular germ cell cancer after elevated pre-
Rago Vittoria, Romeo Francesco, Giordano Francesca, Ferraro Aurora, Andò Sebastiano, Carpino Amalia   +5 more
doaj   +2 more sources

Testicular Embryonal Carcinoma With Retroperitoneal Metastasis and Normal AFP and HCG: A Case Report [PDF]

Case Reports in Oncological Medicine
Testicular germ cell tumors are common malignant tumors in young men, among which embryonal carcinoma, as an important subtype of non-seminomatous germ cell tumors, is usually accompanied by elevated serum tumor markers.
Panpan Teng, Mingxi Yang, Shang Song
doaj   +2 more sources

Diagnosis, treatment, and long-term follow-up of a 13-year-old boy with a testicular mixed germ cell tumor (yolk sac tumor and embryonal carcinoma): a case report and literature review [PDF]

Frontiers in Pediatrics
Testicular germ cell tumors (TGCTs) are rare in children under 15 years of age. We report the first documented case of a mixed yolk sac tumor and embryonal carcinoma in the left testis of a 13-year-old boy in the early stages of puberty (12–14 years ...
Jing Yang, Jianjun Lai, Shiping Zheng, Huanmei Tang   +3 more
doaj   +2 more sources

A rare case of pure-type embryonal carcinoma in a 75-year-old woman mimicking epithelial ovarian carcinoma [PDF]

Kosin Medical Journal, 2022
Embryonal carcinoma, a very rare ovarian germ cell tumor, involves pure and mixed phenotypes. Pure-type embryonal carcinoma has never been reported in postmenopausal women. The current case was, thus, misdiagnosed as an epithelial ovarian carcinoma based
Hyun Been Jo, Eun Taeg Kim, Nam Kyung Lee, Kyung Un Choi, Eon Jin Kim, Yun Joo Shin, Ki Hyung Kim, Dong Soo Suh   +7 more
doaj   +1 more source

Mixed Germ Cell Tumour in an Infertile Male Having Unilateral Cryptorchidism: A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2016
Mixed germ cell tumours with multiple components occur more frequently than the pure varieties of germ cell tumours. Embryonal carcinoma and teratoma together form the most common components of the mixed germ cell tumour but the yolk sac tumour is ...
Anand Singla, Navneet Kaur, Gunjeet Sandhu, Rupesh Nagori   +3 more
doaj   +1 more source

Sacrococcygeal teratoma: evaluation of its approach, treatment and follow-up in two reference children cancer centers in Brazil / Rio de Janeiro

Revista do Colégio Brasileiro de Cirurgiões, 2022
Introduction: sacrococcygeal teratoma (TSC) is the most common tumor of the neonatal period. Alphafetoprotein is an important tumor marker and is used in the follow-up period as a marker of malignancy.
VANESSA DO NASCIMENTO SANTOS, SIMONE DE OLIVEIRA COELHO, ALAN ARAUJO VIEIRA   +2 more
doaj   +2 more sources

Dysgerminoma with Embryonal Carcinoma, a Rare Ovarian Malignant Mixed Germ Cell Tumor in a 13-Year-Old Girl: A Case Report [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
Introduction: Pediatric patients rarely develop ovarian tumors, but mainly develop ovarian germ cell tumors. Malignant germ cell tumors are generally rare and dysgerminoma is the most frequent malignant ovarian neoplasm in young and adolescent girls.
Mahsa Akbari Oryani, Farzaneh Akbari, Marjaneh Farazestanian, Sare Etemad   +3 more
doaj   +1 more source