Results 11 to 20 of about 13,787 (250)

Giant Mediastinal Germ Cell Tumour: An Enigma of Surgical Consideration [PDF]

open access: yesCase Reports in Surgery, 2016
We present a case of 16-year-old male, who was referred from private centre for dyspnoea, fatigue, and orthopnea. The chest radiograph revealed complete opacification of left chest which was confirmed by computed tomography as a large left mediastinal ...
Firdaus Hayati   +5 more
doaj   +2 more sources

To Be or Not to Be a Germ Cell: The Extragonadal Germ Cell Tumor Paradigm [PDF]

open access: yes, 2021
In the human embryo, the genetic program that orchestrates germ cell specification involves the activation of epigenetic and transcriptional mechanisms that make the germline a unique cell population continuously poised between germness and pluripotency.
Massimo De Felici   +11 more
core   +3 more sources

Treatment of clinical stage I non-seminoma

open access: yesAsian Journal of Urology, 2021
Germ cell cancers are the most common solid tumors among men between 15 and 40 years. Non-seminomatous germ cell tumors (NSGCTs) represent a unique and exclusive cohort of germ cell tumor patients. Non-seminoma can harbor different histologic components.
Christian Winter, Andreas Hiester
doaj   +1 more source

Establishment of pluripotent cell lines from vertebrate species - Present status and future prospects [PDF]

open access: yes, 1999
Pluripotent embryonic stem (ES) cells are undifferentiated cell lines derived from early embryos and are capable of unlimited undifferentiated proliferation in vitro.
Vassilieva, Svetlana G.   +4 more
core   +1 more source

What is new about germ cell ovarian tumors? [PDF]

open access: yes, 2022
Germ cell tumors of the ovary are the second most frequently found ovarian neoplasms following epithelial ovarian cancers. It is a heterogeneous group with an origin in a primitive germ cells.
Grabska, Kinga; Students’ Scientific Organization of Cancer Cell Biology, Department of Cancer Prevention, Medical University of Warsaw, Warsaw, Poland   +9 more
core   +1 more source

Chemotherapy-Induced Depletion of OCT4-Positive Cancer Stem Cells in a Mouse Model of Malignant Testicular Cancer

open access: yesCell Reports, 2017
Summary: Testicular germ cell tumors (TGCTs) are among the most responsive solid cancers to conventional chemotherapy. To elucidate the underlying mechanisms, we developed a mouse TGCT model featuring germ cell-specific Kras activation and Pten ...
Timothy M. Pierpont   +15 more
doaj   +1 more source

Management of germ cell tumors in children: Approaches to cure [PDF]

open access: yes, 2002
The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Schneider, D. T.   +9 more
core   +1 more source

The histologic features of intratubular germ cell neoplasia and its correlation with tumor behavior [PDF]

open access: yesInvestigative and Clinical Urology, 2016
Purpose: To assess the prevalence of intratubular germ cell neoplasia (ITGCN) in patients with concurrent testis tumor and its correlation with histologic features and serum tumor markers.
Abbas Basiri   +4 more
doaj   +1 more source

Primary Germ Cell Tumors of the Mediastinum: 10 Years of Experience in a Tertiary Teaching Hospital

open access: yesKaohsiung Journal of Medical Sciences, 2005
Germ cell tumors occur mostly in the gonad. Extragonadal germ cell tumors are rare, and most occur in the retroperitoneum and mediastinum. Primary mediastinal germ cell tumors are often found in the anterior portion of the mediastinum and include ...
Chih-Jen Yang   +2 more
doaj   +1 more source

Epigenetic markers in the embryonal germ cell development and spermatogenesis

open access: yesBasic and Clinical Andrology, 2023
Résumé La spermatogenèse est le processus de génération de cellules reproductrices mâles à partir de cellules souches spermatogoniales, dans l’épithélium séminifère du testicule.
Amadeusz Odroniec   +2 more
doaj   +1 more source

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