Results 11 to 20 of about 13,787 (250)
Giant Mediastinal Germ Cell Tumour: An Enigma of Surgical Consideration [PDF]
We present a case of 16-year-old male, who was referred from private centre for dyspnoea, fatigue, and orthopnea. The chest radiograph revealed complete opacification of left chest which was confirmed by computed tomography as a large left mediastinal ...
Firdaus Hayati +5 more
doaj +2 more sources
To Be or Not to Be a Germ Cell: The Extragonadal Germ Cell Tumor Paradigm [PDF]
In the human embryo, the genetic program that orchestrates germ cell specification involves the activation of epigenetic and transcriptional mechanisms that make the germline a unique cell population continuously poised between germness and pluripotency.
Massimo De Felici +11 more
core +3 more sources
Treatment of clinical stage I non-seminoma
Germ cell cancers are the most common solid tumors among men between 15 and 40 years. Non-seminomatous germ cell tumors (NSGCTs) represent a unique and exclusive cohort of germ cell tumor patients. Non-seminoma can harbor different histologic components.
Christian Winter, Andreas Hiester
doaj +1 more source
Establishment of pluripotent cell lines from vertebrate species - Present status and future prospects [PDF]
Pluripotent embryonic stem (ES) cells are undifferentiated cell lines derived from early embryos and are capable of unlimited undifferentiated proliferation in vitro.
Vassilieva, Svetlana G. +4 more
core +1 more source
What is new about germ cell ovarian tumors? [PDF]
Germ cell tumors of the ovary are the second most frequently found ovarian neoplasms following epithelial ovarian cancers. It is a heterogeneous group with an origin in a primitive germ cells.
Grabska, Kinga; Students’ Scientific Organization of Cancer Cell Biology, Department of Cancer Prevention, Medical University of Warsaw, Warsaw, Poland +9 more
core +1 more source
Summary: Testicular germ cell tumors (TGCTs) are among the most responsive solid cancers to conventional chemotherapy. To elucidate the underlying mechanisms, we developed a mouse TGCT model featuring germ cell-specific Kras activation and Pten ...
Timothy M. Pierpont +15 more
doaj +1 more source
Management of germ cell tumors in children: Approaches to cure [PDF]
The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Schneider, D. T. +9 more
core +1 more source
The histologic features of intratubular germ cell neoplasia and its correlation with tumor behavior [PDF]
Purpose: To assess the prevalence of intratubular germ cell neoplasia (ITGCN) in patients with concurrent testis tumor and its correlation with histologic features and serum tumor markers.
Abbas Basiri +4 more
doaj +1 more source
Primary Germ Cell Tumors of the Mediastinum: 10 Years of Experience in a Tertiary Teaching Hospital
Germ cell tumors occur mostly in the gonad. Extragonadal germ cell tumors are rare, and most occur in the retroperitoneum and mediastinum. Primary mediastinal germ cell tumors are often found in the anterior portion of the mediastinum and include ...
Chih-Jen Yang +2 more
doaj +1 more source
Epigenetic markers in the embryonal germ cell development and spermatogenesis
Résumé La spermatogenèse est le processus de génération de cellules reproductrices mâles à partir de cellules souches spermatogoniales, dans l’épithélium séminifère du testicule.
Amadeusz Odroniec +2 more
doaj +1 more source

