Results 21 to 30 of about 11,863 (162)
LINEing germ and embryonic stem cells’ silencing of retrotransposons [PDF]
Genes & Development, 2014 Almost half of our genome is occupied by transposable elements. Although most of them are inactive, one type of non-long terminal repeat (LTR) retrotransposon, long interspersed nuclear element 1 (LINE1), is capable of retrotransposition. Two studies in this issue, Pezic and colleagues (pp. 1410–1428) and Castro-Diaz and colleagues (pp.
Ishiuchi, Takashi +1 more
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Stem Cell Research, 2018 Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate.
Joanna J. Gell +4 more
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Dysgerminoma with Embryonal Carcinoma, a Rare Ovarian Malignant Mixed Germ Cell Tumor in a 13-Year-Old Girl: A Case Report [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i ĪrānIntroduction: Pediatric patients rarely develop ovarian tumors, but mainly develop ovarian germ cell tumors. Malignant germ cell tumors are generally rare and dysgerminoma is the most frequent malignant ovarian neoplasm in young and adolescent girls.
Mahsa Akbari Oryani +3 more
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Treatment of clinical stage I non-seminoma
Asian Journal of Urology, 2021 Germ cell cancers are the most common solid tumors among men between 15 and 40 years. Non-seminomatous germ cell tumors (NSGCTs) represent a unique and exclusive cohort of germ cell tumor patients. Non-seminoma can harbor different histologic components.
Christian Winter, Andreas Hiester
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A germ cell origin of embryonic stem cells? [PDF]
Development, 2005 Because embryonic stem (ES) cells are generally derived by the culture of inner cell mass (ICM) cells, they are often assumed to be the equivalent of ICM cells. However, various evidence indicates that ICM cells transition to a different cell type during ES-cell derivation.
Thomas P, Zwaka, James A, Thomson
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Cell Reports, 2017 Summary: Testicular germ cell tumors (TGCTs) are among the most responsive solid cancers to conventional chemotherapy. To elucidate the underlying mechanisms, we developed a mouse TGCT model featuring germ cell-specific Kras activation and Pten ...
Timothy M. Pierpont +15 more
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The histologic features of intratubular germ cell neoplasia and its correlation with tumor behavior [PDF]
Investigative and Clinical Urology, 2016 Purpose: To assess the prevalence of intratubular germ cell neoplasia (ITGCN) in patients with concurrent testis tumor and its correlation with histologic features and serum tumor markers.
Abbas Basiri +4 more
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Primary Germ Cell Tumors of the Mediastinum: 10 Years of Experience in a Tertiary Teaching Hospital
Kaohsiung Journal of Medical Sciences, 2005 Germ cell tumors occur mostly in the gonad. Extragonadal germ cell tumors are rare, and most occur in the retroperitoneum and mediastinum. Primary mediastinal germ cell tumors are often found in the anterior portion of the mediastinum and include ...
Chih-Jen Yang +2 more
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Pure Embryonal Cell Carcinoma: A Rare Entity [PDF]
Journal of Clinical and Diagnostic Research, 2023 Malignancy of the testes constitutes only one percent of all male cancers. Most testicular malignancies are Germ Cell Tumours (GCTs), which are broadly categorised into seminomatous and non-seminomatous types. Non seminomatous GCTs are further classified
Neha Jaiswal +2 more
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Embryonic Stem Cells: Testing the Germ-Cell Theory [PDF]
Current Biology, 2011 The exact cellular origin of embryonic stem cells remains elusive. Now a new study provides compelling evidence that embryonic stem cells, established under conventional culture conditions, originate from a transient germ-cell state.
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