Results 21 to 30 of about 13,787 (250)
Pure Embryonal Cell Carcinoma: A Rare Entity [PDF]
Journal of Clinical and Diagnostic Research, 2023 Malignancy of the testes constitutes only one percent of all male cancers. Most testicular malignancies are Germ Cell Tumours (GCTs), which are broadly categorised into seminomatous and non-seminomatous types. Non seminomatous GCTs are further classified
Neha Jaiswal +2 more
doaj +1 more source
Prognostic factors in children with extracranial germ cell tumors treated with cisplatin-based chemotherapy [PDF]
Korean Journal of Pediatrics, 2015 PurposeTo evaluate the outcomes and prognostic factors in children with extracranial germ cell tumors (GCTs) treated at a single institution.MethodsSixty-six children diagnosed with extracranial GCTs between 1996 and 2012 were included in the study ...
Jinsup Kim +7 more
doaj +1 more source
Germ Cell Tumor Presenting with Precocious Puberty in a Girl in United Arab Emirates
Dubai Medical Journal, 2020 We herein report a rare case of malignant mixed germ cell tumor comprising both an embryonal carcinoma (60%) and a yolk sac tumor (40%). A 7-year-old girl presented to the emergency department with persistent vaginal bleeding, abdominal pain, and ...
Asim Noor Rana +4 more
doaj +1 more source
Integrated Molecular Characterization of Testicular Germ Cell Tumors
Cell Reports, 2018 Summary: We studied 137 primary testicular germ cell tumors (TGCTs) using high-dimensional assays of genomic, epigenomic, transcriptomic, and proteomic features. These tumors exhibited high aneuploidy and a paucity of somatic mutations.
Hui Shen +240 more
doaj +1 more source
Malignant Ovarian Mixed Germ Cell Tumor: a Rare Case [PDF]
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2009 Background and Objectives: Mixed germ cell tumors of the ovary, uncommon but aggressive tumors are seen most often in young women or adolescent girls, and are generally curable if found and treated early.
Z. Ebrahimi, Z. Khalaji Nia
doaj +2 more sources
A Case of Sarcoidosis Disseminated to Skeletal Tissues
International Journal of Medical Students, 2013 Sarcoidosis is a systemic granulomatous disease of unknown etiology that typically affects young adults. Diagnostic criteria for sarcoidosis include involvement of two or more of the following organ systems: 1) pulmonary infiltrates; 2) bilateral hilar ...
Edon Rabinowitz +2 more
doaj +1 more source
Formation of neural and epidermal lineages during the differentiation of human embryonal carcinomacells [PDF]
, 2003 Within the ectoderm of the developing human embryo, cell fate determination is largely modulated by factors activated by cell-to-cell signalling. In vertebrates, ectoderm primarily differentiates into neural cells that make up the central nervous system ...
Christie, Victoria Buyers
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Signalling events controlling early cell fate decisions in a human embryonal carcinoma cell line, with relation to neural versus non-neural transitions m human ectoderm development [PDF]
, 2007 In this study the human embryonal carcinoma cell line TERA2.cl.spl2 (TERA2.spl2) was utilised as an in vitro model in which to study mechanisms governing neural versus non- neural transitions in the human ectoderm.
Horrocks, Grace Mary
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source