Results 21 to 30 of about 21,086 (311)

The histologic features of intratubular germ cell neoplasia and its correlation with tumor behavior [PDF]

Investigative and Clinical Urology, 2016
Purpose: To assess the prevalence of intratubular germ cell neoplasia (ITGCN) in patients with concurrent testis tumor and its correlation with histologic features and serum tumor markers.
Abbas Basiri, Saeed Movahhed, Mahmood Parvin, Maziar Salimi, Gholam Hossein Rezaeetalab   +4 more
doaj   +1 more source

Primary Germ Cell Tumors of the Mediastinum: 10 Years of Experience in a Tertiary Teaching Hospital

Kaohsiung Journal of Medical Sciences, 2005
Germ cell tumors occur mostly in the gonad. Extragonadal germ cell tumors are rare, and most occur in the retroperitoneum and mediastinum. Primary mediastinal germ cell tumors are often found in the anterior portion of the mediastinum and include ...
Chih-Jen Yang, Meng-Shuan Cheng, Ming-Shyan Huang   +2 more
doaj   +1 more source

Identification of side population cells in mouse primordial germ cells and prenatal testis [PDF]

, 2011
In mammals, the stem cells of spermatogenesis are derived from an embryonic cell population called primordial germ cells (PGCs). Spermatogonial stem cells displaying the "side population" (SP) phenotype have been identified in the immature and adult ...
De Felici, Massimo, Fera, Stefania, Grisanti, Laura, Lucia Scaldaferri, Maria, Sanchez, Massimo, Stefanini, Mario, Vicini, Elena   +6 more
core   +2 more sources

Exploring the interdependencies of research funders in the UK [PDF]

, 2014
Investment in medical research is vital to the continuing improvement of the UK's health and wealth. It is through research that we expand our understanding of disease and develop new treatments for patients.
Crane, P, Farrell, C, Garau, M, Grassano, N, Hernandez-Villafuerte, K, Hopkins, M M, Hutton, J, Lang, F, Mawer, A, Pateman, C, Rotolo, D, Shah, K, Sharp, T, Sussex, J   +13 more
core   +1 more source

Hematopoietic progenitors express embryonic stem cell and germ layer genes [PDF]

Comptes Rendus. Biologies, 2011
Cell therapy for tissue regeneration requires cells with high self-renewal potential and with the capacity to differentiate into multiple differentiated cell lineages, like embryonic stem cells (ESCs) and adult somatic cells induced to pluripotency (iPSCs) by genetic manipulation.
Bernard, Pessac, Mehdi Ait, Bara, David, Ford, Gopi K, Patibandla, David, Trisler   +4 more
openaire   +2 more sources

Pure Embryonal Cell Carcinoma: A Rare Entity [PDF]

Journal of Clinical and Diagnostic Research, 2023
Malignancy of the testes constitutes only one percent of all male cancers. Most testicular malignancies are Germ Cell Tumours (GCTs), which are broadly categorised into seminomatous and non-seminomatous types. Non seminomatous GCTs are further classified
Neha Jaiswal, Anita Sajjanar, Vaishnavi Mishra   +2 more
doaj   +1 more source

Primate Primordial Germ Cells Acquire Transplantation Potential by Carnegie Stage 23. [PDF]

, 2017
Primordial germ cells (PGCs) are the earliest embryonic progenitors in the germline. Correct formation of PGCs is critical to reproductive health as an adult.
Chen, Di, Clark, Amander T, Gkountela, Sofia, Hennebold, Jon D, Liu, Wanlu, Orwig, Kyle E, Sosa, Enrique, Sukhwani, Meena   +7 more
core   +2 more sources

Giant Mediastinal Germ Cell Tumour: An Enigma of Surgical Consideration

Case Reports in Surgery, 2016
We present a case of 16-year-old male, who was referred from private centre for dyspnoea, fatigue, and orthopnea. The chest radiograph revealed complete opacification of left chest which was confirmed by computed tomography as a large left mediastinal ...
Firdaus Hayati, Nurayub Mohd Ali, Levin Kesu Belani, Nornazirah Azizan, Andee Dzulkarnaen Zakaria, Mohd Ramzisham Abdul Rahman   +5 more
doaj   +1 more source

Specific detection of OCT3/4 isoform A/B/B1 expression in solid (germ cell) tumours and cell lines: Confirmation of OCT3/4 specificity for germ cell tumours [PDF]

, 2011
Background: OCT3/4 (POU5F1) is an established diagnostic immunohistochemical marker for specific histological variants of human malignant germ cell tumours (GCTs), including the seminomatous types and the stem cell component of non-seminomas, known as ...
A J M Gillis, A M Hoogland, AJ Gillis, AT Collins, BR Krishnan, CJ Lengner, D Pain, DC Hay, DM Lai, G J L H van Leenders, G Jenster, G Suo, H A D M van Herk, H Niwa, H Stoop, H Zaehres, J de Jong, J de Jong, J de Jong, J de Jong, J de Jong, J Kehler, J Lee, J Martens, J Takeda, JM Velkey, JW Oosterhuis, KJ Livak, L Cheng, L H J Looijenga, L Looijenga, L Poliseno, L Ricci-Vitiani, LH Looijenga, LHJ Looijenga, M A Rijlaarsdam, M Pesce, M Pesce, M Timmermans, MH Asadi, MH Tai, MM Matin, N Xu, NJ van Casteren, P Sotomayor, PW Andrews, RA Sturm, RB Marques, S Liedtke, S Liedtke, S Zhao, SI Papamichos, SK Hussain, T Cantz, UI Ezeh, V Botquin, W Dinjens, WM van Weerden, X Wang, Y Atlasi, Y Atlasi, Y Gao, YC Chen   +62 more
core   +3 more sources

Evaluating Human Embryonic Germ Cells: Concord and Conflict as Pluripotent Stem Cells

Stem Cells, 2005
AbstractThe realization of cell replacement therapy derived from human pluripotent stem cells requires full knowledge of the starting cell types as well as their differentiated progeny. Alongside embryonic stem cells, embryonic germ cells (EGCs) are an alternative source of pluripotent stem cell. Since 1998, four groups have described the derivation of
Turnpenny, Lee W., Spalluto, Cosma M., Perrett, Rebecca M., O'Shea, Marie, Piper Hanley, Karen, Cameron, Iain T., Wilson, David I., Hanley, Neil A.   +7 more
openaire   +4 more sources