Results 31 to 40 of about 11,863 (162)
Transitioning from human primordial germ cells to embryonic germ cells
Stem Cell ReportsPrimordial germ cells (PGCs) can give rise to pluripotent embryonic germ cells (EGCs) in rodents. Leitch and colleagues in this issue successfully derived human EGC-like cells from PGC-like cells and applied comprehensive multi-omic profiling to resolve their pluripotent and epigenetic dynamics, providing new insights into potential mechanisms ...
Kenyu Iwatsuki, Yasuhiro Takashima
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Entry of Mouse Embryonic Germ Cells into Meiosis
Developmental Biology, 1997 Germ cells harvested from mouse embryonic genital ridges were mixed with disaggregated embryonic lung cells, and the reaggregates were cultured for 4-7 days. Germ cells derived from female embryos 10.5-13.5 days postcoitum (dpc) entered and progressed through meiotic prophase in vitro as in vivo, although with a 12- to 24-hr delay. If the cultures were
McLaren, A., Southee, D.
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Giant Mediastinal Germ Cell Tumour: An Enigma of Surgical Consideration
Case Reports in Surgery, 2016 We present a case of 16-year-old male, who was referred from private centre for dyspnoea, fatigue, and orthopnea. The chest radiograph revealed complete opacification of left chest which was confirmed by computed tomography as a large left mediastinal ...
Firdaus Hayati +5 more
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Prognostic factors in children with extracranial germ cell tumors treated with cisplatin-based chemotherapy [PDF]
Korean Journal of Pediatrics, 2015 PurposeTo evaluate the outcomes and prognostic factors in children with extracranial germ cell tumors (GCTs) treated at a single institution.MethodsSixty-six children diagnosed with extracranial GCTs between 1996 and 2012 were included in the study ...
Jinsup Kim +7 more
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AKT signaling promotes derivation of embryonic germ cells from primordial germ cells [PDF]
Development, 2008 Primordial germ cells (PGCs) are embryonic germ cell precursors. Although the developmental potency of PGCs is restricted to the germ lineage, PGCs can acquire pluripotency, as verified by the in vitro establishment of embryonic germ (EG) cells and the in vivo production of testicular teratomas.
Kimura, Tohru +7 more
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Germ cells from mouse and human embryonic stem cells [PDF]
Reproduction, 2006 Abstract Mammalian gametes are derived from a founder population of primordial germ cells (PGCs) that are determined early in embryogenesis and set aside for unique development. Understanding the mechanisms of PGC determination and differentiation is important for elucidating causes of infertility and how endocrine disrupting ...
Behrouz, Aflatoonian, Harry, Moore
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Germ Cell Tumor Presenting with Precocious Puberty in a Girl in United Arab Emirates
Dubai Medical Journal, 2020 We herein report a rare case of malignant mixed germ cell tumor comprising both an embryonal carcinoma (60%) and a yolk sac tumor (40%). A 7-year-old girl presented to the emergency department with persistent vaginal bleeding, abdominal pain, and ...
Asim Noor Rana +4 more
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Integrated Molecular Characterization of Testicular Germ Cell Tumors
Cell Reports, 2018 Summary: We studied 137 primary testicular germ cell tumors (TGCTs) using high-dimensional assays of genomic, epigenomic, transcriptomic, and proteomic features. These tumors exhibited high aneuploidy and a paucity of somatic mutations.
Hui Shen +240 more
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Malignant Ovarian Mixed Germ Cell Tumor: a Rare Case [PDF]
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2009 Background and Objectives: Mixed germ cell tumors of the ovary, uncommon but aggressive tumors are seen most often in young women or adolescent girls, and are generally curable if found and treated early.
Z. Ebrahimi, Z. Khalaji Nia
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A Case of Sarcoidosis Disseminated to Skeletal Tissues
International Journal of Medical Students, 2013 Sarcoidosis is a systemic granulomatous disease of unknown etiology that typically affects young adults. Diagnostic criteria for sarcoidosis include involvement of two or more of the following organ systems: 1) pulmonary infiltrates; 2) bilateral hilar ...
Edon Rabinowitz +2 more
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