Results 31 to 40 of about 12,778 (301)
The histologic features of intratubular germ cell neoplasia and its correlation with tumor behavior [PDF]
Investigative and Clinical Urology, 2016 Purpose: To assess the prevalence of intratubular germ cell neoplasia (ITGCN) in patients with concurrent testis tumor and its correlation with histologic features and serum tumor markers.
Abbas Basiri +4 more
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Pure Embryonal Cell Carcinoma: A Rare Entity [PDF]
Journal of Clinical and Diagnostic Research, 2023 Malignancy of the testes constitutes only one percent of all male cancers. Most testicular malignancies are Germ Cell Tumours (GCTs), which are broadly categorised into seminomatous and non-seminomatous types. Non seminomatous GCTs are further classified
Neha Jaiswal +2 more
doaj +1 more source
Primary Germ Cell Tumors of the Mediastinum: 10 Years of Experience in a Tertiary Teaching Hospital
Kaohsiung Journal of Medical Sciences, 2005 Germ cell tumors occur mostly in the gonad. Extragonadal germ cell tumors are rare, and most occur in the retroperitoneum and mediastinum. Primary mediastinal germ cell tumors are often found in the anterior portion of the mediastinum and include ...
Chih-Jen Yang +2 more
doaj +1 more source
Embryonic Stem Cells: Testing the Germ-Cell Theory [PDF]
Current Biology, 2011 The exact cellular origin of embryonic stem cells remains elusive. Now a new study provides compelling evidence that embryonic stem cells, established under conventional culture conditions, originate from a transient germ-cell state.
openaire +2 more sources
Transitioning from human primordial germ cells to embryonic germ cells
Stem Cell ReportsPrimordial germ cells (PGCs) can give rise to pluripotent embryonic germ cells (EGCs) in rodents. Leitch and colleagues in this issue successfully derived human EGC-like cells from PGC-like cells and applied comprehensive multi-omic profiling to resolve their pluripotent and epigenetic dynamics, providing new insights into potential mechanisms ...
Kenyu Iwatsuki, Yasuhiro Takashima
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Entry of Mouse Embryonic Germ Cells into Meiosis
Developmental Biology, 1997 Germ cells harvested from mouse embryonic genital ridges were mixed with disaggregated embryonic lung cells, and the reaggregates were cultured for 4-7 days. Germ cells derived from female embryos 10.5-13.5 days postcoitum (dpc) entered and progressed through meiotic prophase in vitro as in vivo, although with a 12- to 24-hr delay. If the cultures were
McLaren, A., Southee, D.
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What is new about germ cell ovarian tumors?
, 2022 Germ cell tumors of the ovary are the second most frequently found ovarian neoplasms following epithelial ovarian cancers. It is a heterogeneous group with an origin in a primitive germ cells.
Grabska, Kinga; Students’ Scientific Organization of Cancer Cell Biology, Department of Cancer Prevention, Medical University of Warsaw, Warsaw, Poland +4 more
core +1 more source
Prognostic factors in children with extracranial germ cell tumors treated with cisplatin-based chemotherapy [PDF]
Korean Journal of Pediatrics, 2015 PurposeTo evaluate the outcomes and prognostic factors in children with extracranial germ cell tumors (GCTs) treated at a single institution.MethodsSixty-six children diagnosed with extracranial GCTs between 1996 and 2012 were included in the study ...
Jinsup Kim +7 more
doaj +1 more source
AKT signaling promotes derivation of embryonic germ cells from primordial germ cells [PDF]
Development, 2008 Primordial germ cells (PGCs) are embryonic germ cell precursors. Although the developmental potency of PGCs is restricted to the germ lineage, PGCs can acquire pluripotency, as verified by the in vitro establishment of embryonic germ (EG) cells and the in vivo production of testicular teratomas.
Kimura, Tohru +7 more
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Germ cells from mouse and human embryonic stem cells [PDF]
Reproduction, 2006 Abstract Mammalian gametes are derived from a founder population of primordial germ cells (PGCs) that are determined early in embryogenesis and set aside for unique development. Understanding the mechanisms of PGC determination and differentiation is important for elucidating causes of infertility and how endocrine disrupting ...
Behrouz, Aflatoonian, Harry, Moore
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