Results 121 to 130 of about 1,521,712 (329)
Long-term survival and morbidity in patients with metastatic malignant germ cell tumors treated with cisplatin-based combination chemotherapy [PDF]
, 1986 Sophie D. Fosså +4 more
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Expert Perspective: Diagnosis and Treatment of Castleman Disease
Arthritis &Rheumatology, Accepted Article.Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen +2 more
wiley +1 more source
Supporting doctors' professional identity development through specialist training
Anatomical Sciences Education, EarlyView.Abstract Anatomy‐centric specialties such as surgery, radiology, and anatomical pathology (AP) have workforce shortages, with attrition during the training phase proposed as a contributing factor. Current understanding of the reasons behind trainee attrition is limited, and there have been calls to increase the depth and richness of research in this ...
Shemona Y. Rozario +3 more
wiley +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT OCT4 plays a crucial role in the DNA damage response(DDR) mechanism, whereas cisplatin (CDDP) acts as an anti‐tumor agent by inducing DDR. This study aimed to investigate the role of OCT4 in regulating DNA methyltransferase 1 (DNMT1) in CDDP‐treated gastric cancer (GC).
Zhengzheng Yan +6 more
wiley +1 more source
Approaches to repurposing reverse transcriptase antivirals in cancer
British Journal of Clinical Pharmacology, EarlyView.This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head +2 more
wiley +1 more source
Germ Cell Tumors in the Mediastinum
Magna MedikaBackground: Germ mediastinum tumors grow in the mediastinum and consist of teratoma, seminoma, and nonseminomatous. Cases of germ mediastinum tumors are rare. During the last decade, only two cases have been found at Dr.
Muhammad Harris Sis Sulthansyah +1 more
doaj +1 more source
BMEMat, EarlyView.This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan +12 more
wiley +1 more source
The ductal network in the human testis and epididymis: What belongs to which?
Clinical Anatomy, EarlyView.Abstract The testes and epididymis are traversed by a system of tubules in which sperm cells are generated, matured, nourished, and transported. Among these are the efferent ductules, which connect the rete testis to the duct of the epididymis. In the Terminologia Anatomica (TA), the efferent ductules are assigned to the testicles, while numerous ...
Andreas Gocht +3 more
wiley +1 more source
JURNAL BIOMEDIK (JBM), 2013 Abstract: Germ cell tumors of the ovary are primary ovarian tumors which derived from primitive germinal cells. These tumors are derived from primitive germinal cells. The total incidence of these tumors is around 30% of all tumors, and are mostly found in children and young adults. The etiology and pathogenesis of these tumors are not clearly defined,
openaire +3 more sources