Results 131 to 140 of about 5,730,128 (298)

Metabolomic investigation of cisplatin‐induced acute kidney injury in paediatric cancer patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Cisplatin causes acute kidney injury (AKI) in approximately 46% of paediatric cancer patients who receive it. Serum creatinine (SCr) is a poor biomarker of cisplatin nephrotoxicity, because there is a delay between cisplatin infusion and SCr elevation.
Yong Jin Lim, Amy Thachil, Kelly McMahon, Ross T. Tsuyuki, S. Rod Rassekh, Lesley G. Mitchell, Prasad Devarajan, Cherry Mammen, Bruce C. Carleton, Geoffrey D. E. Cuvelier, Victor A. Lewis, Colin J. D. Ross, Alexandra P. Zorzi, Sylvain Baruchel, Raveena Ramphal, Eric Bouffet, Mathieu Lemaire, Tom D. Blydt‐Hansen, Brad L. Urquhart, The Applying Biomarkers to Minimize Long‐Term Effects of Childhood/Adolescent Cancer Treatment (ABLE) Research Study Group, Tom Blydt‐Hansen, Bruce C. Carleton, Geoff D. E. Cuvelier, Sunil Desai, Prasad Devarajan, Conrad Fernandez, Adam Fleming, Paul Gibson, Caroline Laverdiere, Victor Lewis, Mary L. McBride, Bruno Michon, Shahrad Rod Rassekh, Colin J. D. Ross, Christine Sabapathy, Kirk R. Schultz, Michael Zappitelli, Alexandra Zorzi   +37 more
wiley   +1 more source

Malignant sacrococcygeal germ cell tumors in children: a 30-year experience from a single institution

, 2013
Background. Our aim was to analyze treatment results and survival characteristics of our patients with malignant sacrococcygeal germ cell ...
Kale, GÜLSEV, EKİNCİ, SANİYE, KUPELI, Serhan, AKYÜZ, CANAN, YALCIN, Sule, Buyukpamukcu, MÜNEVVER, YALÇIN, BİLGEHAN, VARAN, ALİ, KUTLUK, Tezer   +8 more
core   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Germ Cell Tumors in the Mediastinum

Magna Medika
Background:  Germ mediastinum tumors grow in the mediastinum and consist of teratoma, seminoma, and nonseminomatous. Cases of germ mediastinum tumors are rare. During the last decade, only two cases have been found at Dr.
Muhammad Harris Sis Sulthansyah, Lilik Lestari   +1 more
doaj   +1 more source

MAGE-A4, a germ cell specific marker, is expressed differentially in testicular tumors

, 2001
Testicular germ cell tumors are the most common malignancy in young males, and the frequency of these tumors has risen dramatically over the last century. Because it is known that the MAGE genes are expressed in a wide variety of tumors but are expressed
Rioux-Leclercq, N, Satie, A P, Rajpert-De Meyts, E, Aubry, F, Samson, M, Jégou, B, Chomez, P, De Backer, O, Spagnoli, G C   +8 more
core  

Single-Institution Experience with 25 Cases of Extragonadal Germ Cell Tumors

Extragonadal germ cell tumors are rare and have a poorer prognosis compared to testicular germ cell tumors. Although the therapeutic options are similar to those for advanced testicular germ cell tumors, there is uncertainty regarding the efficacy of ...
山根, 武紘, 渡邊, 岳之, 北, 悠希, 澤田, 篤郎, 増井, 仁彦, 後藤, 崇之, 小林, 恭, 松岡, 崇志, 赤松, 秀輔, 佐野, 剛視, 河野, 仁   +10 more
core   +1 more source

Surgical management of primary central nervous system germ cell tumors

, 2010
The successful treatment of children with a primary CNS germ cell tumor can be greatly influenced by the neurosurgeon involved in the diagnostic and therapeutic care of these children.
Mark D. Krieger, Mark M. Souweidane, Howard L. Weiner, Jonathan L. Finlay   +3 more
core   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Germ cell tumors of the mediastinum [PDF]

Interactive CardioVascular and Thoracic Surgery, 2010
Dimos, Karangelis, Georgia, Kalafati, Vasileios, Liouras, Nikolaos, Tsilimingas   +3 more
openaire   +2 more sources

Probiotic spore‐based bioresponsive drug delivery for reversing inflammatory bowel disease and its associated anxiety and depression

BMEMat, EarlyView.
A probiotic spore‐based drug delivery system (BCS‐Que@ApNPs) provides excellent targeted delivery, bioresponsive drug release, and long‐term retention (over 48 h), making it suitable for oral treatment of inflammatory bowel disease and its associated anxiety and depression.
Qingling Song, Beiyang Xue, Yao Li, Chuangxi Zhou, Junfei Yang, Yunfei Li, Lingwen Ding, Yun Zhang, Hongjuan Zhao, Lei Wang   +9 more
wiley   +1 more source