Results 101 to 110 of about 5,730,128 (298)

Histopathological analysis of testicular tumors

Journal of Pathology of Nepal, 2012
Background: Testicular cancers are rare in most countries. However, in many western countries its incidence has been increasing since the middle of the twentieth century. A definite geographic and racial distribution is seen in testicular tumors.
S Karki, RR Bhatta
doaj   +1 more source

PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation [PDF]

, 2018
Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate.
Timothy J. Hunt, Gell, Joanna J, Zhao, Jasmine, Hunt, Timothy J, Chen, Di, Clark, Amander T, Joanna J. Gell, Di Chen, Jasmine Zhao, Amander T. Clark   +9 more
core   +1 more source

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

Advanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu, Jingbo Dong, Qiufang Gong, Xuejiao Song, Zhifa Shen, Chao Liang   +5 more
wiley   +1 more source

Epigenetics and testicular germ cell tumors [PDF]

, 2018
Malignant testicular germ cell tumors (TGCTs) are the most frequent testicular cancers in Caucasian males, developing at the most productive age of man. We are briefly reviewing TGCT-tumorigenesis with an emphasis on epigenetics.
Buljubašić, Robert, Vlahović, Maja, Maja Buljubašić, Robert Buljubašić, Floriana Bulić-Jakuš, Nino Sinčić, Ana Katušić Bojanac, Bojanac, Ana Katušić, Davor Ježek, Maja Vlahović, Ulamec, Monika, Bulić-Jakuš, Floriana, Buljubašić, Maja, Ježek, Davor, Monika Ulamec, Sinčić, Nino   +15 more
core   +1 more source

Oral Actinomyces Species Exposure is Associated with Anxiety‐Like Behavior, Mitochondrial Remodeling, and Altered GABAergic Pathways

Advanced Science, EarlyView.
Oral exposure to cannabis‐associated Actinomyces species, particularly A. meyeri, is associated with anxiety‐like behavior in mice in the absence of detectable bacterial translocation or overt systemic inflammation. These findings support a potential oral‐brain metabolic axis involving candidate metabolites such as arginine and argininosuccinate ...
Tabinda Salman, Zhenwu Luo, Douglas Johnson, Arshad A. Noorani, Zhuang Wan, Bogdan Bordieanu, Zhi‐wei Ye, Rachel D. Penrod, Hongxu Xian, Sylvia Fitting, Peter W. Kalivas, Wei Jiang   +11 more
wiley   +1 more source

GERM

, 2014
Ce carnet a pour objet de présenter les activités du GERM et annoncer les événements et publications en rapport avec ce groupe. Le Groupe d’enseignement et de recherche sur les Mayas et la Mésoamérique (GERM), groupe de recherche du LESC (UMR 7186), a ...
germ
core  

Gliomas, germ cell tumors, and craniopharyngioma

, 2021
This report summarizes the current multimodality treatment approaches for children with low- and high-grade gliomas, germinoma, and nongerminomatous germ cell tumors, and craniopharyngiomas used in the Children's Oncology Group (COG) and the ...
MacDonald, Shannon, Ladra, Matthew, Murphy, Erin, Alapetite, Claire, Campbell, Shauna, Poppe, Matthew, Aridgides, Paul, Braunstein, Steve, Haas-Kogan, Daphne, Janssens, Geert O, MS Radiotherapie, Cancer   +11 more
core  

Intratumoral Fusogenic Outer Membrane Vesicles Enhance Antitumor Immunity Through Tumor MHC‐I Upregulation and Tumor Bacterization

Advanced Science, EarlyView.
Tumor bacterization by fusogenic outer membrane vesicles enhances microbial‐like recognition of tumor cells while activating the TLR4–NF‐κB–NLRC5 axis to upregulate MHC class I expression. By simultaneously strengthening APC sensing and T‐cell recognition, this strategy breaks tumor immune invisibility and promotes more effective antitumor immune ...
Xing Liu, Jiaxin Zhou, Guihong Lu, Chenjing Zhao, Weixiu Wang, Jichuan Chen, Fengqi Zhang, Fan Zhang, Hai‐Yan Xie, Weidong Nie   +9 more
wiley   +1 more source

Large Oncosomes Induce Pro‐Metastatic Stromal‐Myeloid Reprogramming

Advanced Science, EarlyView.
Large oncosomes systemically reprogram bone marrow mesenchymal stem cells through innate nucleic acid sensing, driving inflammatory and immunosuppressive remodeling that supports a metastasis‐permissive bone marrow environment, revealing a novel tumor‐host communication axis in cancer. ABSTRACT Bone metastasis can be facilitated by systemic remodeling,
Taylon Felipe Silva, Virginia Marcia Concato‐Lopes, Fatima Bedier, Lauren Newman, Diana Kitka, Jamelle Brown, Blandine Victor, Minhyung Kim, Tatyana Vagner, Catherine Grasso, Dmitriy Sheyn, Sungyong You, Michael R. Freeman, Fayyaz S. Sutterwala, Helen S. Goodridge, Caroline Jefferies, Paola de Candia, Jlenia Guarnerio, Dolores Di Vizio   +18 more
wiley   +1 more source

Bilateral Testicular Tumors Recurred 5 Years After Surgery for an Extragonadal Germ Cell Tumor: Case Report

IJU Case Reports
Introduction Extragonadal germ cell tumors (EGCT) account for approximately 3%–7% of all germ cell tumors. Metachronous testicular tumors develop in 5%–7% of patients after EGCT treatment; however, bilateral testicular tumors have not been reported. Case
Hiraku Yamamoto, Isao Hara, Satoshi Muraoka, Takahito Wakaymiya, Shimpei Yamashita, Yasuo Kohjimoto   +5 more
doaj   +1 more source