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Extragonadal germ cell tumours

International Urology and Nephrology, 1988
In a retrospective study of patients treated for germ cell tumours, the authors found seven patients with primary extragonadal tumours in the retroperitoneum. These tumours are, in terms of histology, identical with germ cell tumours of the testis. The disease manifests itself by pain in the kidney region, palpable abdominal mass, weight loss, fever ...
M, Hornák, D, Ondrus
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Testicular germ cell tumours

The Lancet, 2016
Testicular germ cell tumours are at the crossroads of developmental and neoplastic processes. Their cause has not been fully elucidated but differences in incidences suggest that a combination of genetic and environment factors are involved, with environmental factors predominating early in life.
Ewa, Rajpert-De Meyts   +4 more
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Testicular germ cell tumours

BMJ, 2013
#### Summary points Testicular germ cell cancer affects mainly young men, with 85% presenting between 15 and 44 years of age. The incidence of this disease is increasing—the lifetime risk for a man is now about one in 200 in the United Kingdom.1 Presentation is usually with a painless lump.
Alan, Horwich   +2 more
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Germ cell tumours of the testis

Critical Reviews in Oncology/Hematology, 2005
Cancer of the testis is a relatively rare disease, accounting for about 1% of all cancers in men. Cryptorchidism is the only confirmed risk factor for testicular germ cell tumour. The majority of GCT are clinically detectable at initial presentation. Any nodular, hard, or fixed area discovered in the testis, must be considered neoplastic until proved ...
Gori S   +5 more
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Are cranial germ cell tumours really tumours of germ cells?

Neuropathology and Applied Neurobiology, 2006
Germ cell tumours of the brain and those that occur in the gonads are believed to share a common origin from germ cell progenitors. This ‘germ cell theory’ rests upon similar histopathology between these tumours in different locations and the belief that endogenous somatic cells of the brain could not give rise to the range of cell types seen in germ ...
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Update in germ cell tumours

Current Opinion in Oncology, 2015
The purpose of this study is to update the reader on advances in postpubertal male germ cell tumours (GCTs) over the last 18 months.Single nucleotide polymorphisms, including in four sex-determination genes, have been identified as additional genetic susceptibility loci to testicular GCT development. New insights into cisplatin resistance implicate the
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Germ Cell Tumours

Annales de pathologie, 1986
Germ cell tumours in children may arise in any part of the reproductive tract or in ectopic sites determined by patterns of development in embryological life. If malignant change occurs in the germ cells, dysgerminoma, teratoma or yolk sac tumour may result.
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Germ cell tumours of the testis

Clinical Radiology, 1966
An analysis is made of 263 cases of germ cell tumours of the testis presenting in the Liverpool Region, and the various treatment policies used over a 15 year period are compared. A family history of malignancy, testicular pain, a long history prior to treatment, delay in irradiating the abdominal glands following orchidectomy and ectopic testis were ...
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Germ-cell tumours

1992
The occurrence of primary germ-cell tumours, both benign and malignant, in the mediastinum is now well documented. The usual location of these tumours is the anterior mediastinum and histologically they are identical to those originating in the genital organs (Patcher and Lattes, 1963).
J. M. Verley, K. H. Hollmann
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Germ cell tumours of the testis

The Journal of Pathology, 1983
AbstractThe application of new techniques, particularly the identification of tumour markers, in the study of testicular germ cell tumours is presently leading to a reassessment of opinions regarding the origin and classification of these neoplasms. Some aspects of this controversy are examined.
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