Results 251 to 260 of about 5,138,444 (292)
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Germ-Cell Tumours

2020
Abstract Germ-cell tumours (GCT) comprise a heterogeneous group of tumours, occurring mainly in children, adolescents, and young adults, which vary by site, range of histological subtypes, and behaviour. Gonadal sites, testes, and ovaries account for around two thirds of extracranial GCT, the remainder occurring at extragonadal sites.
Gabriele Calaminus, James C. Nicholson
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Germ cell tumours

2010
Chapter 8.14 covers germ cell tumours, including germinoma, embryonal carcinoma, yolk sac tumour, choriocarcinoma, and teratomas.
Frank Gaillard   +2 more
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Germ cell tumours

2017
Abstract Central nervous system germ cell tumours are mysterious tumours, which are common in young male adults in eastern Asia, and include germinoma, mature and immature teratoma, teratoma with malignant transformation, yolk sac tumour, embryonal carcinoma, choriocarcinoma, and mixed tumours of these components.
Claire Alapetite   +2 more
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Germ cell tumours in a brother and sister

Acta Paediatrica, 1997
In familial germ cell tumour cases, a normal chromosomal karyotype pattern is rare. We report the findings of germ cell tumours in two siblings with a normal chromosomal karyotype. One of these patients had dysgerminoma in the right ovary and was treated successfully for this. At present, she is 23 years old and has two daughters.
C, Akyüz   +4 more
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The treatment of cranial germ cell tumours

Cancer Treatment Reviews, 2000
Germ cell tumours of the central nervous system (CNS) include many subtypes whose response to treatment varies, even though the symptoms and radiological appearances are similar. Five-year survival rates are 96% for germinomas, 100% for mature teratomas, 67% for immature teratomas and 69% for immature teratomas mixed with germinomas; for beta-HCG ...
A A, Brandes   +2 more
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Bilateral Germ Cell Tumours of the Testis

British Journal of Urology, 1980
Summary— Between 1952 and 1976, 760 men with testicular tumours were seen at The Royal Marsden Hospital. Of this group 21 (2.75%) developed tumours of the contralateral testis, in 2 instances synchronously and in the remaining 19 at intervals from 4 months to 15 years.
M, Sokal, M J, Peckham, W F, Hendry
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Germ cell tumours

2003
Abstract Germ cell tumours (GCT) are a heterogeneous group of tumours presenting in all age groups including neonates; occurring in a wide range of sites; behaving as entirely benign through to highly malignant; having a variable and intriguing histology; and probably developing from at least two pathogenetic pathways and cell lines ...
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Pathogenesis of Testicular Germ Cell Tumours

European Urology, 1993
Testicular germ cell tumours are subdivided clinically into two major groups: seminomas and non-seminomatous germ cell tumours (NSGCT). The relationship of seminomas to NSGCT remains controversial. The pathogenesis of NSGCT has been studied experimentally in mice, but there are no adequate experimental models of seminomas in laboratory rodents ...
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Germ Cell Tumour

1990
Teilum (1959) first drew attention to the histological features of a tumour originally described by Schiller in 1939 as mesonephroma, which had a close structural resemblance to the rat placenta. He thought this structural display was an attempt at extra-embryonic differentiation; the tumour was therefore of germ cell origin.
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Oral Etoposide in Germ Cell Tumours

Drugs, 1999
Patients with germ cell tumours who relapse or fail to achieve disease-free status after first-line chemotherapy have a poor prognosis. When administered orally, etoposide produces responses in approximately 25% of patients whose disease is refractory to therapy and is a reasonable choice for palliative treatment in patients who are otherwise incurable.
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