piRNAs and Aubergine cooperate with Wispy poly(A) polymerase to stabilize mRNAs in the germ plasm [PDF]
, 2017 Piwi-interacting RNAs (piRNAs) and PIWI proteins play a crucial role in germ cells by repressing transposable elements and regulating gene expression. In Drosophila, maternal piRNAs are loaded into the embryo mostly bound to the PIWI protein Aubergine ...
Beilharz, Traude H. +9 more
core +3 more sources
Bmp4 is required for the generation of primordial germ cells in the mouse embryo.
Genes & Development, 1999 In many organisms the allocation of primordial germ cells (PGCs) is determined by the inheritance of maternal factors deposited in the egg. However, in mammals, inductive cell interactions are required around gastrulation to establish the germ line. Here,
K. Lawson +7 more
semanticscholar +1 more source
Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors [PDF]
, 2010 Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells.
Abel, M.H. +4 more
core +2 more sources
Tre1, a G protein-coupled receptor, directs transepithelial migration of Drosophila germ cells.
PLoS Biology, 2003 In most organisms, germ cells are formed distant from the somatic part of the gonad and thus have to migrate along and through a variety of tissues to reach the gonad.
Prabhat S Kunwar +4 more
doaj +1 more source
Establishment of pluripotent cell lines from vertebrate species - Present status and future prospects [PDF]
, 1999 Pluripotent embryonic stem (ES) cells are undifferentiated cell lines derived from early embryos and are capable of unlimited undifferentiated proliferation in vitro.
Prelle, Katja +4 more
core +1 more source
Cell cycle regulation for meiosis in mammalian germ cells
The Journal of Reproduction and Development, 2023 In mouse fetal gonads, germ cell development is accompanied by changes in cell cycle mode in response to external signals and intrinsic mechanisms of cells.
Ryuki SHIMADA, Kei-ichiro ISHIGURO
doaj +1 more source
Primary Culture System for Germ Cells from Caenorhabditis elegans Tumorous Germline Mutants
Bio-Protocol, 2017 The Caenorhabditis elegans germ line is an important model system for the study of germ stem cells. Wild-type C. elegans germ cells are syncytial and therefore cannot be isolated in in vitro cultures. In contrast, the germ cells from tumorous mutants can
Alexandra Vagasi +3 more
doaj +1 more source
Chick stem cells: Current progress and future prospects. [PDF]
, 2013 Chick embryonic stem cells (cESCs) can be derived from cells obtained from stage X embryos (blastoderm stage); these have the ability to contribute to all somatic lineages in chimaeras, but not to the germ line. However, lines of stem cells that are able
Intarapat, S, Stern, CD
core +1 more source
Primate Primordial Germ Cells Acquire Transplantation Potential by Carnegie Stage 23. [PDF]
, 2017 Primordial germ cells (PGCs) are the earliest embryonic progenitors in the germline. Correct formation of PGCs is critical to reproductive health as an adult.
Chen, Di +7 more
core +2 more sources
CPEB3 Maintains Developmental Competence of the Oocyte
CellsMammalian oocyte development depends on the temporally controlled translation of maternal transcripts, particularly in the coordination of meiotic and early embryonic development when transcription has ceased.
Lucie Lamacova +9 more
doaj +1 more source