High-Speed Mouse Backcrossing Through the Female Germ Line. [PDF]
PLoS ONE, 2016 Transferring mouse mutations into specific mouse strain backgrounds can be critical for appropriate analysis of phenotypic effects of targeted genomic alterations and quantitative trait loci.
Erin Grove +2 more
doaj +1 more source
Prospects for transgenesis in the chick [PDF]
, 2004 Research to develop a useful method for genetic modification of the chick has been on-going since the first demonstrations in the mouse in the 1980s that genetic modification is an invaluable tool for the study of gene function. Manipulation of the chick
Sang, Helen
core +1 more source
Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Environmentally induced transgenerational epigenetic reprogramming of primordial germ cells and the subsequent germ line. [PDF]
PLoS ONE, 2013 A number of environmental factors (e.g. toxicants) have been shown to promote the epigenetic transgenerational inheritance of disease and phenotypic variation.
Michael K Skinner +5 more
doaj +1 more source
Advances in Sustainable and Wearable Textile Based Soft Robotics
Advanced Functional Materials, EarlyView.This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas +6 more
wiley +1 more source
The translational repressor Cup is required for germ plasm assembly and germ cell development in Drosophila. [PDF]
, 2011 RNA localization is a cellular mechanism used to localize proteins to sub-cellular domains and to control protein synthesis regionally. In oocytes, RNA localization has profound implications for development, generating asymmetric protein distributions ...
Ottone, Cristina
core +1 more source
Evidence against a germ plasm in the milkweed bug Oncopeltus fasciatus, a hemimetabolous insect
Biology Open, 2013 Summary Primordial germ cell (PGC) formation in holometabolous insects like Drosophila melanogaster relies on maternally synthesised germ cell determinants that are asymmetrically localised to the oocyte posterior cortex.
Ben Ewen-Campen +2 more
doaj +1 more source
Séminaire GERM - Marie Ramelet : "Emballer, empaqueter, envelopper chez les Mayas" - 25/02/2021
, 2021 La prochaine séance (zoom) du GERM est prévue le jeudi 25 février de 14h30 à 16h30. A cette occasion, nous recevrons Marie Ramelet, doctorante à l’université de Paris 1/Archam qui nous présentera les avancées de son travail de thèse.
germ
core
Advanced Healthcare Materials, EarlyView.A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi +10 more
wiley +1 more source
Primary Culture System for Germ Cells from Caenorhabditis elegans Tumorous Germline Mutants
Bio-Protocol, 2017 The Caenorhabditis elegans germ line is an important model system for the study of germ stem cells. Wild-type C. elegans germ cells are syncytial and therefore cannot be isolated in in vitro cultures. In contrast, the germ cells from tumorous mutants can
Alexandra Vagasi +3 more
doaj +1 more source