Results 71 to 80 of about 4,398,636 (256)
Advanced Science, EarlyView.In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao +6 more
wiley +1 more source
, 2016 Le mardi 27 septembre 2016, de 11h à 13h Nous avons le plaisir de vous inviter à la réunion du GERM et le GDRI RITMO. Nous nous réunirons pour faire le point sur le prochain colloque de Rome, un bilan de l’atelier d’Izamal sur les rituels de fondation ...
germ
core
Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Unusual coexistence of a renal anomaly and germ cell tumor: An embryonal happenstance?
Indian Journal of Medical and Paediatric Oncology, 2012 The germ cell lines and kidney develop in close proximity in a similar embronic period. The extragonadal germ cell tumors and horseshoe kidney both are the result of abnormal migration of two germ line cells.
Ankita Nachankar +6 more
doaj +1 more source
Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module
Advanced Science, EarlyView.Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang +6 more
wiley +1 more source
Advanced Science, EarlyView.Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li +23 more
wiley +1 more source
, 2016 Le vendredi 7 octobre 2016, de 10h00 à 12h Nous avons le plaisir de vous inviter à la réunion du GERM et du GDRI RITMO consacrée à l’étude et au commentaire de deux textes (un en archéologie, un en ethnographie) portant sur les rituels de (re)fondation ...
germ
core
Advanced Science, EarlyView.This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu +9 more
wiley +1 more source
Séance du GERM/RITMO (20/02/2017)
, 2017 Le vendredi 20 février 2017, de 9h30 à 13h Nous avons le plaisir de vous inviter à la réunion du GERM et du GDRI RITMO pour trois communications et leur discussion, "Rapports de l'Homme à l'espace domestique en Terres Mayas : diversités des pratiques et ...
germ
core
Advanced Science, EarlyView.SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long +12 more
wiley +1 more source