Results 101 to 110 of about 3,848,803 (345)

Egotism in German Philosophy. [PDF]

open access: green, 1917
Ralph Barton Perry, George Santayana
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Zur Stellung des Deutschen auf dem europäischen Arbeitsmarkt [PDF]

open access: yesLinguistische Treffen in Wrocław
For some time now, there has been a trend for German studies programs to be adapted to the needs of students on the one hand, and to the needs of the job market on the other.
Joanna Szczęk
doaj   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

RRS "Charles Darwin" Cruise 169, 17 Feb-19 Mar 2005. Hydrothermal exploration of the southern Mid-Atlantic Ridge [PDF]

open access: yes, 2006
The principal objective of this cruise was to identify the first site or sites of high temperature hydrothermal venting anywhere on the southern Mid-Atlantic Ridge, to characterize their geological setting, preliminary chemical nature and to identify ...
German, C.R., Parson, L.M.
core  

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Phrasem-Konstruktionen im deutsch-polnischen Vergleich anhand des Projekts „A Multilingual Repository of Phraseme Constructions in Central and Eastern European Languages (PhraConRep)“ (CA22115) [PDF]

open access: yesLinguistische Treffen in Wrocław
When learning and using a foreign language, language users must not only adhere to the grammatical rules of a particular language, but also have knowledge of which words occur together.
Dominika Janus   +3 more
doaj   +1 more source

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