Results 91 to 100 of about 1,449,585 (331)

Interaktion und Innovation – Studie zur Übersetzung deutschsprachiger Literatur in der Zeitschrift Ausländische Literatur und Kunst (1978–2022)

open access: yesInterkulturelles Forum der deutsch-chinesischen Kommunikation
Die Literaturzeitschrift Ausländische Literatur und Kunst erschien zum ersten Mal 1978 im Shanghai Translation Publishing House und gilt seitdem als eine anerkannte Fachzeitschrift für fremdsprachige Literatur in China.
She Lihui, Zhang Fan
doaj   +1 more source

“Everything has already happened!”: the first Russian translation of the poem by Paul Henry Gerber

open access: yesСлово.ру: балтийский акцент
The paper is the first translation into Russian of the poem ‘Everything has already hap­pened! (Epistle to Julius Stettenheim)’ by the outstanding German scholar, professor at the University of Königsberg, medical practitioner and poet Paul Henry Gerber (
Lada V. Syrovatko
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Brazilian literature written in German, and its criticism

open access: yesPandaemonium Germanicum: Revista de Estudos Germanísticos, 2016
This text aims to divulge a chronological and commented panorama of the critical studies published about the literature produced by German-speaking immigrants and their descendants in Brazil, arguing that this is a partial critique.
Celeste Ribeiro de Sousa
doaj  

“I’ll Be All Right in a Few Moments”: Alienation, Isolation, and Family Dynamics in Franz Kafka’s The Metamorphosis

open access: yesKorpusgermanistik
Kafka's The Metamorphosis effectively explores themes of workplace alienation, urban isolation, and family dynamics within the Modern era, employing a range of literary devices and techniques, such as rhetorical questioning, imagery, and parallelism, to ...
Megan Varney
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Strange Bedfellows and Their Grandchildren: German Literature as Evidence and Confession of Reunification

open access: yes, 2011
From Hegel to Merkel, from Bismarck to BMW, German culture has defined and re-defined itself through a cycle of reaction; thesis, antithesis, synthesis.
Rosenberg, Cory H.
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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