Results 141 to 150 of about 41,715 (245)

DNMT3A-dependent DNA methylation shapes the endothelial enhancer landscape. [PDF]

Nucleic Acids Res
Gehrs S, Gu Z, Hey J, Weichenhan D, Buckwalter N, Jakab M, Hotz-Wagenblatt A, Breuer K, Prada ML, Hübschmann D, Schlereth K, Plass C, Augustin H.   +12 more
europepmc   +1 more source

Multimodal Investigation of Angiogenesis and Its Prevention by Small Compounds in a Zebrafish Cancer Model

Advanced Science, EarlyView.
A combined optical coherence tomography angiography and fluorescence imaging approach assesses tumor angiogenesis and drug effects in a novel zebrafish cancer model. By analyzing 3D vasculature data, the two imaging methods complement each other to quantify blood flow, vessel structure, and drug efficacy.
Marco Andreana, Ryan Sentosa, Caterina Sturtzel, Martin Pfister, René Werkmeister, Anna Schmitt, David Traver, Rainer Leitgeb, Wolfgang Drexler, Martin Distel, Angelika Unterhuber   +10 more
wiley   +1 more source

A benchmark study of compression software for human short-read sequence data. [PDF]

Sci Rep
Betschart RO, Thalén F, Blankenberg S, Zoche M, Zeller T, Ziegler A.   +5 more
europepmc   +1 more source

Natural Allelic Variations in IbCHYR1–IbZnFR Complex Regulate Fusarium Root Rot Resistance in Sweet Potato

Advanced Science, EarlyView.
FfRlpA2, a conserved Fusarium effector, functions as a protease inhibitor by hijacking the E3 ubiquitin ligase IbCHYR1 to degrade the resistance factor IbZnFR, thereby promoting Fusarium pathogenicity. Conversely, the high dosage Pro::IbZnFRHap2 allele was associated with resistance to root rot disease.
Huan Zhang, Zhuoru Dai, Xiaochen Zhang, Meiqi Shang, Xiaoru Gao, Ruiqi Ma, Limeng Zhao, Xiaoli Zhang, Qingchang Liu, Hong Zhai, Shaopei Gao, Ning Zhao, Qinghe Cao, Qiang Li, Shaozhen He   +14 more
wiley   +1 more source

Genomic and Cis‐Regulatory Basis of a Plastic C3‐C4 Photosynthesis in Eleocharis Baldwinii

Advanced Science, EarlyView.
The sedge Eleocharis baldwinii remarkably switches between C3‐like and C4‐like photosynthesis in response to environmental conditions. Combining gap‐free genome assembly with single‐cell multi‐omics, this study uncovers how subgenome dominance and cell‐specific cis‐regulation enable C4 photosynthesis.
Lu Chen, Yanfeng Jia, Zaihui Zhou, Qiying Jiang, Jianlin Liu, Jianhui Gu, Chuan Chen, Shujing Cheng, Jinfang Chu, Xin Liu, Yongjun Lin, Xiang Li   +11 more
wiley   +1 more source

Correction: Toward a Domain-Overarching Metadata Schema for Making Health Research Studies FAIR (Findable, Accessible, Interoperable, and Reusable): Development of the NFDI4Health Metadata Schema.

JMIR Med Inform
Abaza H, Shutsko A, Klopfenstein SAI, Vorisek CN, Schmidt CO, Brünings-Kuppe C, Clemens V, Darms J, Hanß S, Intemann T, Jannasch F, Kasbohm E, Lindstädt B, Löbe M, Nimptsch K, Nöthlings U, Ocanto MG, Osei TB, Perrar I, Peters M, Pischon T, Sax U, Schulze MB, Schwarz F, Schwedhelm C, Thun S, Waltemath D, Zeleke AA, Müller W, Golebiewski M.   +29 more
europepmc   +1 more source

Application of diagnostic criteria in paediatric complex regional pain syndrome: a scoping review protocol. [PDF]

BMJ Open
Tham SW, Lee R, Rau LM, Sethna NF, Nylander EM, Fabrizi L, Wager J, Koechlin H.   +7 more
europepmc   +1 more source

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

Advanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao, Zhen Li, Ming‐Jie Zhao, Shu‐Ying Li, Qing Xia, Shuoyu Xu, Yu Zhang, Yi Wang, Fang Li, Yu‐Ling Liu, Yun‐Hui Guo, Ruo‐Xi Xu, Han Zhou, Hong Zhou, Wen‐Wen Ding, Yong‐Chen Wang, Yanying Miao, Zhongfeng Wang   +17 more
wiley   +1 more source

Social prescribing to improve health and well-being of patients presenting with non-medical health related social needs in primary care: Study protocol of a multi-center randomized controlled pragmatic feasibility trial. [PDF]

PLoS One
Napierala H, Jeske N, Roll S, Köberlein-Neu J, Herrmann WJ.   +4 more
europepmc   +1 more source

Split‐Aperture Xolography – Linear Volumetric Photoactivation with Short Axial Dimension and Low out of Focus Excitation

Advanced Science, EarlyView.
Stepwise excitation of dual‐color responsive molecules in a novel intersecting half‐cone geometry provides excellent spatial resolution while retaining the high efficiency and thus speed of the overall process. The approach provides volumetric methods with an enhanced performance at the nanoscale.
Martin Regehly, Stefan Hecht
wiley   +1 more source