Results 191 to 200 of about 29,593 (220)

Prolonged Inflammation Associates With Greater Infarct Size and Poor Outcome After ST-Segment Elevation Myocardial Infarction. [PDF]

JACC Basic Transl Sci
Graesser C, Krefting J, Schwab M, Scheidhauer H, Novacek S, Armbruster NL, Hinterdobler J, Rapelius S, Romer A, Rumpf PM, Roski F, Lenz T, Voll F, Vilne B, Trenkwalder T, von Scheidt M, Xhepa E, Joner M, Cassese S, Steffens S, Weber C, Schunkert H, Ndrepepa G, Kastrati A, Kessler T, Moggio A, Sager HB.   +26 more
europepmc   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

Advanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du, Yinming Li, Ziyue Li, Yuedan Wang, Shaopeng Li, Yijie Wang, Yingying Qu, Bingyang Lv, Ying Li, Ting Chen, Yu Zhou, Xuan Xiao   +11 more
wiley   +1 more source

Leveraging Large Language Models to Improve the Readability of German Online Medical Texts: Evaluation Study. [PDF]

JMIR AI
Miftaroski A, Zowalla R, Wiesner M, Pobiruchin M.   +3 more
europepmc   +1 more source

Imaging‐Guided Live Single‐Cell Lipid Profiling of Leader and Follower Cells During Collective Migration of Triple‐Negative Breast Cancer Cells

Advanced Science, EarlyView.
Integrated single‐cell mass spectrometry reveals distinct lipidomic signatures that differentiate leader and follower phenotypes in migratory breast cancer cells. Phenotype‐specific alterations across various lipid classes, including fatty acids and phosphatidylcholines, underpin functional heterogeneity.
Xiaoyue Huang, Judit González Riera, Mai Nguyen, Jeremy Broekhuis, Sylvia E. Le Dévédec, Ahmed Ali, Thomas Hankemeier   +6 more
wiley   +1 more source

Prognostic factors for pediatric sudden sensorineural hearing loss: a systematic review and meta-analysis. [PDF]

Front Pediatr
Wu Z, Zhang P, Sun J, Diao M.
europepmc   +1 more source

Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression

Advanced Science, EarlyView.
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren, Xiaogang Li, Hao Li, Zenghui Cao, Mengtian Hou, Chunlei Zhao, Nan Lou, Sasa Hu, Yanzhe Li, Qian Ma, Yaoyao Li, Yi Fan, Kunkun Zhao, Kai Zhao, Ding Qiu, Fangping Gong, Zhongfeng Li, Haitao Liu, Xingli Ma, Xingxiang Wang, Dongmei Yin   +20 more
wiley   +1 more source

Correction: Toward a Domain-Overarching Metadata Schema for Making Health Research Studies FAIR (Findable, Accessible, Interoperable, and Reusable): Development of the NFDI4Health Metadata Schema. [PDF]

JMIR Med Inform
Abaza H, Shutsko A, Klopfenstein SAI, Vorisek CN, Schmidt CO, Brünings-Kuppe C, Clemens V, Darms J, Hanß S, Intemann T, Jannasch F, Kasbohm E, Lindstädt B, Löbe M, Nimptsch K, Nöthlings U, Ocanto MG, Osei TB, Perrar I, Peters M, Pischon T, Sax U, Schulze MB, Schwarz F, Schwedhelm C, Thun S, Waltemath D, Zeleke AA, Müller W, Golebiewski M.   +29 more
europepmc   +1 more source

In vivo single-cell RNA metabolic labeling resolves early transcriptional responders in the regenerating zebrafish heart. [PDF]

Nat Commun
Mintcheva J, Tseng TL, Goumenaki P, Neuschulz A, Senoussi A, Lelek S, Lim KL, Ming Z, Schäfer R, Hnatiuk A, Ninov N, Beisaw A, McGrail M, Lai SB, Panáková D, Stainier DYR, Junker JP.   +16 more
europepmc   +1 more source

Lessons learned from implementing FAIRification workflows in diabetes research in Germany. [PDF]

PLOS Digit Health
Inau ET, Dedié A, Anastasova I, Schick R, Fröhlich B, Roden M, Birkenfeld AL, de Angelis MH, Preusse M, Waltemath D, Zeleke AA.   +10 more
europepmc   +1 more source

Heterozygous RAB3A variants cause cerebellar ataxia by a partial loss-of-function mechanism. [PDF]

Brain
Hengel H, Hannan SB, Reich S, Beijer D, Roller J, Gilsbach BK, Gloeckner CJ, Greene D, Timmann D, Depienne C, Mumford A, O'Driscoll M, Nemeth AH, Lundberg J, Rodan LH, Bruel AL, Delanne J, Deconinck T, Baets J, Gan-Or Z, Rouleau G, Suchowersky O, Estiar MA, Reich S, Toro C, Züchner S, Hazan J, Pétursson H, Harmuth F, Bauer C, Bauer P, Turro E, Lambright D, Schöls L, Synofzik M.   +34 more
europepmc   +1 more source